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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
subcutaneous injection into stomach
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<blockquote data-quote="Cataceous" data-source="post: 233428" data-attributes="member: 38109"><p>This is demonstrably false. We have the clinical trials involving Xyosted, with total N probably getting into the hundreds now. It would be readily apparent if more than a few percent had the kind of problem you are reporting. In fact the total absorption as measured via AUC was found to be comparable to IM injections. You should expect skepticism, as there's not a known mechanism by which a significant fraction of testosterone can just disappear, assuming it was properly injected. Did you meticulously inspect for injection site leakage? This may be more common with SC delivery. Although less likely, a significant drop in SHBG would manifest in lower total testosterone, without a change in free testosterone. Another scenario with lower probability is that your rate of absorption with SC runs counter to what's typical, and is faster than with IM. However, it would need to be particularly out of the ordinary to produce such results with EOD injections.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 233428, member: 38109"] This is demonstrably false. We have the clinical trials involving Xyosted, with total N probably getting into the hundreds now. It would be readily apparent if more than a few percent had the kind of problem you are reporting. In fact the total absorption as measured via AUC was found to be comparable to IM injections. You should expect skepticism, as there's not a known mechanism by which a significant fraction of testosterone can just disappear, assuming it was properly injected. Did you meticulously inspect for injection site leakage? This may be more common with SC delivery. Although less likely, a significant drop in SHBG would manifest in lower total testosterone, without a change in free testosterone. Another scenario with lower probability is that your rate of absorption with SC runs counter to what's typical, and is faster than with IM. However, it would need to be particularly out of the ordinary to produce such results with EOD injections. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
subcutaneous injection into stomach
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