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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Subcutaneous Administration of Testosterone
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<blockquote data-quote="JSayaMD" data-source="post: 1842" data-attributes="member: 282"><p>IF... "sawtooth" is the goal, agree with low SHBG a smaller more frequent injection is ideal.</p><p></p><p>IF... "sawtooth" is the goal, disagree that with a high SHBG a ONCE weekly larger injection would be better...IF sawtooth pattern is the goal...then sticking with the more frequent injections (same pharmacodynamics = same sawtooth pattern), but just slightly HIGHER dosing with each injection to overcome or "mass action" over the SHBG would seem preferred. Keeps same sawtooth pattern as with lower SHBG (due to not changing injection frequency), but overcomes SHBG to produce adequate free T levels. You can have your cake (keep same sawtooth pattern) and eat it too (overcome the high SHBG to optimize free T)!</p><p></p><p>Dr Saya</p></blockquote><p></p>
[QUOTE="JSayaMD, post: 1842, member: 282"] IF... "sawtooth" is the goal, agree with low SHBG a smaller more frequent injection is ideal. IF... "sawtooth" is the goal, disagree that with a high SHBG a ONCE weekly larger injection would be better...IF sawtooth pattern is the goal...then sticking with the more frequent injections (same pharmacodynamics = same sawtooth pattern), but just slightly HIGHER dosing with each injection to overcome or "mass action" over the SHBG would seem preferred. Keeps same sawtooth pattern as with lower SHBG (due to not changing injection frequency), but overcomes SHBG to produce adequate free T levels. You can have your cake (keep same sawtooth pattern) and eat it too (overcome the high SHBG to optimize free T)! Dr Saya [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Subcutaneous Administration of Testosterone
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