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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Strange results -- About 4 months on TRT protocol
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<blockquote data-quote="Tgrappler" data-source="post: 123734" data-attributes="member: 26924"><p>Hello all, I'll try to explain the situation as simply as I can. I'm 39, very active until recently because of complete lack of energy and started gaining weight, injuries. I used to train muay thai, wrestling and brazilian jiu jitsu pretty much daily since I was in my teens. In the last year I stared getting rather bad panic attacks and my energy levels have disappeared. With that came nagging depressing and isolation. Loss of interest in every day things. But I knew I was not depressed. Something was "missing". On April 27 of this year I got my first lab work to check hormonal imbalances. Lab work was done at Quest Diagnostics:</p><p></p><p>Free Test = 43 (Range 46.0-224.0 pg/mL)</p><p>SHBG = 66 (Range 10-50 nmol/L)</p><p>Bio Test = 87 (Range 110.0-575.0 ng/dL)</p><p>Estradiol = 33 (Range < OR = 29 pg/mL)</p><p></p><p>No surprise that my doc said "man, you really are running on empty". On 5/22 I started on TRT cream. 1ml for the first month 0.5 x 2 times / day. Then 0.5 ml / day. I did that from May - August. Also Estrogen blockers (I swear I could feel some benefit from just taking those alone). AI I would take for the first couple of weeks only total of 16 pills maybe. I used Compounded cream with Lipo (200mg/ml concentration) .. One thing I didn't like about the cream was that this particular batch was very flaky and not at all smooth when I'd rub it on. I was sure about 20-30% didn't really get absorbed.</p><p>Still I felt a pretty solid difference in my energy mood and sleep patterns. Overall I was happy with the results. I was able to restart my training routine and although it took some time to get back into the groove of things, I was able to get back to working out pretty hard at 2-3 times a week and walking (bad kneed) for 5 miles each day.</p><p></p><p>About a month ago I went on a five day trip and didn't bring the cream with me (just forgot). Around the last day I felt rather shitty and one interesting side effect was really bad insomnia, I rarely experienced insomnia in my life. Typical problems would be anxiety and depression. I simply would not fall asleep. Once I got back from the trip and started to reapply the cream as directed things seemingly improved.</p><p>However, within a week or so I ran out of cream and got sick (unrelated). I couldn't get my lab done until about 10 days after I ran out. Here are my numbers as of the most recent test. Same exact lab, same ranges and even the same person taking my blood <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /></p><p></p><p>Free Test = 35</p><p>SHBG = 76</p><p>Bio Test = 76</p><p>Estradiol = 32</p><p></p><p>This does not look promising. By the time second week without cream was coming to an end, I couldn't get off the couch. Walking around the block seemed like torture. Insomnia was nasty, feelings of complete emptiness and hopelessness mixed with non-stop anxiety got a little too much. My doc is really quite good. He did all the right tests and said all the right things. After I texted him saying that I'm seriously at the end of my wits, he pushed a new batch of cream the same day.</p><p>This batch is a lot better, much smoother and within 2 days I feel more stable and my energy and sleep have come back. On Sunday I just slept all day. My body was beyond exhausted. It literally felt like a car without gas.</p><p></p><p>Is it possible to completely lose all the benefits of treatment within 10 days or so? I presume my levels didn't shift significantly, although I probably improved a little while applying the cream.</p><p></p><p>I realize that I messed up because I got the lab work done late, but I would at least hope slightly better numbers. My only conclusion is that initial treatment had a little effect, which wore off rather quickly and levels dropped (and raised) back to where they were because there wasn't that much improvement in the first place?</p></blockquote><p></p>
[QUOTE="Tgrappler, post: 123734, member: 26924"] Hello all, I'll try to explain the situation as simply as I can. I'm 39, very active until recently because of complete lack of energy and started gaining weight, injuries. I used to train muay thai, wrestling and brazilian jiu jitsu pretty much daily since I was in my teens. In the last year I stared getting rather bad panic attacks and my energy levels have disappeared. With that came nagging depressing and isolation. Loss of interest in every day things. But I knew I was not depressed. Something was "missing". On April 27 of this year I got my first lab work to check hormonal imbalances. Lab work was done at Quest Diagnostics: Free Test = 43 (Range 46.0-224.0 pg/mL) SHBG = 66 (Range 10-50 nmol/L) Bio Test = 87 (Range 110.0-575.0 ng/dL) Estradiol = 33 (Range < OR = 29 pg/mL) No surprise that my doc said "man, you really are running on empty". On 5/22 I started on TRT cream. 1ml for the first month 0.5 x 2 times / day. Then 0.5 ml / day. I did that from May - August. Also Estrogen blockers (I swear I could feel some benefit from just taking those alone). AI I would take for the first couple of weeks only total of 16 pills maybe. I used Compounded cream with Lipo (200mg/ml concentration) .. One thing I didn't like about the cream was that this particular batch was very flaky and not at all smooth when I'd rub it on. I was sure about 20-30% didn't really get absorbed. Still I felt a pretty solid difference in my energy mood and sleep patterns. Overall I was happy with the results. I was able to restart my training routine and although it took some time to get back into the groove of things, I was able to get back to working out pretty hard at 2-3 times a week and walking (bad kneed) for 5 miles each day. About a month ago I went on a five day trip and didn't bring the cream with me (just forgot). Around the last day I felt rather shitty and one interesting side effect was really bad insomnia, I rarely experienced insomnia in my life. Typical problems would be anxiety and depression. I simply would not fall asleep. Once I got back from the trip and started to reapply the cream as directed things seemingly improved. However, within a week or so I ran out of cream and got sick (unrelated). I couldn't get my lab done until about 10 days after I ran out. Here are my numbers as of the most recent test. Same exact lab, same ranges and even the same person taking my blood :) Free Test = 35 SHBG = 76 Bio Test = 76 Estradiol = 32 This does not look promising. By the time second week without cream was coming to an end, I couldn't get off the couch. Walking around the block seemed like torture. Insomnia was nasty, feelings of complete emptiness and hopelessness mixed with non-stop anxiety got a little too much. My doc is really quite good. He did all the right tests and said all the right things. After I texted him saying that I'm seriously at the end of my wits, he pushed a new batch of cream the same day. This batch is a lot better, much smoother and within 2 days I feel more stable and my energy and sleep have come back. On Sunday I just slept all day. My body was beyond exhausted. It literally felt like a car without gas. Is it possible to completely lose all the benefits of treatment within 10 days or so? I presume my levels didn't shift significantly, although I probably improved a little while applying the cream. I realize that I messed up because I got the lab work done late, but I would at least hope slightly better numbers. My only conclusion is that initial treatment had a little effect, which wore off rather quickly and levels dropped (and raised) back to where they were because there wasn't that much improvement in the first place? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Strange results -- About 4 months on TRT protocol
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