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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Stop Using Mouthwash And Dental Hygiene
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<blockquote data-quote="FunkOdyssey" data-source="post: 273466" data-attributes="member: 44064"><p>The link between dental health and erectile function is real, however, inflammation is the main character in the story, not a deficiency of nitrate-reducing bacteria:</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/[/URL]</p><p></p><p></p><p></p><p><em><span style="font-size: 12px">Our meta-analysis revealed a statistically significant association between PD and ED, based on the summarized results of six observational studies (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr5-15579883211007277" target="_blank">Chou et al., 2018</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr10-15579883211007277" target="_blank">Keller et al., 2012</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr17-15579883211007277" target="_blank">Martín et al., 2018</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr21-15579883211007277" target="_blank">Oğuz et al., 2013</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr30-15579883211007277" target="_blank">Tsao et al., 2015</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr32-15579883211007277" target="_blank">Zadik et al., 2009</a>), with 38675 cases and 1,76,333 controls.</span></em></p><p><em><span style="font-size: 12px"></span></em></p><p><em><span style="font-size: 12px">PD and ED share risk factors such as age, obesity, smoking, diabetes mellitus, metabolic syndrome, hypertension, cardiovascular diseases, and excessive drinking (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr16-15579883211007277" target="_blank">Machado et al., 2020</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr34-15579883211007277" target="_blank">Zuo et al., 2011</a>). Both, also share common pathophysiological pathways, including endothelial dysfunction and inflammation (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr12-15579883211007277" target="_blank">Kulshrestha et al., 2020</a>). The evidence is strengthened by the findings that smoking cessation, reduction of obesity, and avoiding other common risk factors are safe and effective means to reduce the incidence of both diseases. <strong>Evidence support the statement that providing periodontal treatment can reduce the risk of ED</strong> (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr8-15579883211007277" target="_blank">Eltas et al., 2013</a>). Endothelial dysfunction is a possible explanation for the association between PD and ED. It has been confirmed in experimental and clinical studies that PD could impair vascular endothelial dysfunction (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr1-15579883211007277" target="_blank">Amar et al., 2003</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr2-15579883211007277" target="_blank">Blum et al., 2007</a>) by increasing the expression of proinflammatory cytokines and adhesion molecules. In addition, <strong>PD induce a mild systematic inflammatory status and decrease the activity of endothelial nitric oxide synthase and nitric oxide synthase in penile cavernous tissues of rats</strong> (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr12-15579883211007277" target="_blank">Kulshrestha et al., 2020</a>; Pedrotti et al.; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr34-15579883211007277" target="_blank">Zuo et al., 2011</a>). <strong>Periodontal therapy may improve damaged vascular endothelial function </strong>and results in significant improvement in the function (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr9-15579883211007277" target="_blank">Gurav, 2014</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr24-15579883211007277" target="_blank">Scannapieco et al., 2010</a>). Another possible suggestion for the link between PD and ED could be via the level of testosterone (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr6-15579883211007277" target="_blank">Corona et al., 2008</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr7-15579883211007277" target="_blank">Corona & Maggi, 2010</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr27-15579883211007277" target="_blank">Singh et al., 2011</a>; <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr29-15579883211007277" target="_blank">Steffens et al., 2020</a>).</span></em></p><p></p><p>If you were dependent on nitrite from your oral bacteria for nitric oxide production, you would have erectile dysfunction whenever you weren't eating nitrate-rich foods, which for many people, would be most of the time. Remember, the list of high nitrate foods is a short one: leafy greens, beets, a few other vegetables, and processed meats. If you don't eat significant quantitates of these key vegetables, and you don't eat processed meat every day, you aren't getting much nitrate in your diet.</p><p></p><p>There are millions of people going through life without regularly consuming any significant source of dietary nitrate and they have perfect erectile function. Carnivores that don't eat processed meat make a good example. These people will go years with no dietary nitrate, and yet everything is functioning normally.</p><p></p><p>If the strongest link between dental health and erectile function involves gum disease rather than nitrate-reducing oral bacteria, how does that affect our opinions of mouthwash? If you ask me, we should be prescribing Listerine for better erections, not avoiding it.</p></blockquote><p></p>
[QUOTE="FunkOdyssey, post: 273466, member: 44064"] The link between dental health and erectile function is real, however, inflammation is the main character in the story, not a deficiency of nitrate-reducing bacteria: [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/[/URL] [I][SIZE=12px]Our meta-analysis revealed a statistically significant association between PD and ED, based on the summarized results of six observational studies ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr5-15579883211007277']Chou et al., 2018[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr10-15579883211007277']Keller et al., 2012[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr17-15579883211007277']Martín et al., 2018[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr21-15579883211007277']Oğuz et al., 2013[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr30-15579883211007277']Tsao et al., 2015[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr32-15579883211007277']Zadik et al., 2009[/URL]), with 38675 cases and 1,76,333 controls. PD and ED share risk factors such as age, obesity, smoking, diabetes mellitus, metabolic syndrome, hypertension, cardiovascular diseases, and excessive drinking ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr16-15579883211007277']Machado et al., 2020[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr34-15579883211007277']Zuo et al., 2011[/URL]). Both, also share common pathophysiological pathways, including endothelial dysfunction and inflammation ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr12-15579883211007277']Kulshrestha et al., 2020[/URL]). The evidence is strengthened by the findings that smoking cessation, reduction of obesity, and avoiding other common risk factors are safe and effective means to reduce the incidence of both diseases. [B]Evidence support the statement that providing periodontal treatment can reduce the risk of ED[/B] ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr8-15579883211007277']Eltas et al., 2013[/URL]). Endothelial dysfunction is a possible explanation for the association between PD and ED. It has been confirmed in experimental and clinical studies that PD could impair vascular endothelial dysfunction ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr1-15579883211007277']Amar et al., 2003[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr2-15579883211007277']Blum et al., 2007[/URL]) by increasing the expression of proinflammatory cytokines and adhesion molecules. In addition, [B]PD induce a mild systematic inflammatory status and decrease the activity of endothelial nitric oxide synthase and nitric oxide synthase in penile cavernous tissues of rats[/B] ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr12-15579883211007277']Kulshrestha et al., 2020[/URL]; Pedrotti et al.; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr34-15579883211007277']Zuo et al., 2011[/URL]). [B]Periodontal therapy may improve damaged vascular endothelial function [/B]and results in significant improvement in the function ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr9-15579883211007277']Gurav, 2014[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr24-15579883211007277']Scannapieco et al., 2010[/URL]). Another possible suggestion for the link between PD and ED could be via the level of testosterone ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr6-15579883211007277']Corona et al., 2008[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr7-15579883211007277']Corona & Maggi, 2010[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr27-15579883211007277']Singh et al., 2011[/URL]; [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142012/#bibr29-15579883211007277']Steffens et al., 2020[/URL]).[/SIZE][/I] If you were dependent on nitrite from your oral bacteria for nitric oxide production, you would have erectile dysfunction whenever you weren't eating nitrate-rich foods, which for many people, would be most of the time. Remember, the list of high nitrate foods is a short one: leafy greens, beets, a few other vegetables, and processed meats. If you don't eat significant quantitates of these key vegetables, and you don't eat processed meat every day, you aren't getting much nitrate in your diet. There are millions of people going through life without regularly consuming any significant source of dietary nitrate and they have perfect erectile function. Carnivores that don't eat processed meat make a good example. These people will go years with no dietary nitrate, and yet everything is functioning normally. If the strongest link between dental health and erectile function involves gum disease rather than nitrate-reducing oral bacteria, how does that affect our opinions of mouthwash? If you ask me, we should be prescribing Listerine for better erections, not avoiding it. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Stop Using Mouthwash And Dental Hygiene
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