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Just want to add that my wife started at 1 click and was advised by Dr. Saya to be able to go up a click after 2 weeks if no response, not exceeding 3 clicks.  She recently had her first 3 month follow up and had been on three clicks for 2 months.  Total test was around 190, free 8, which I thought was high.  Dr Saya however thought that it was OK as long as there were no side effects, which there have been none.  She continues on 3 clicks.  No amazing results yet but some improvements.  She is also now beginning with natures thyroid as well so still some things to work out.