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It's just creating a lot more stability and consistency with your serum levels at 2x/wk ... Peak value is usually at the 2 to 3 day range, 1/2 life being 7 to 8 days. Reducing to 2x per week will reduce the peaks and troughs (as you know); with a continuous administration of smaller dosages during the "peak" window. Another key benefit is that lowering these spikes will also help with keeping estradiol managed, as downstream conversion will be also be noticeably more stable. No AI in three (3) years on this end ... It works!