Spinal Cord Injuries (SCI) and Testosterone

Will Brink

Member
In prior posts, I have discussed my hypothesis that growth hormone and related growth factors, as a possible therapy for connective tissue/joint degeneration in active populations. The study below finds testosterone therapy (TRT ) appears highly valuable treatment in SCI; to prevent the loss of skeletal muscle post SCI. These results do not surprise me in the least and why this is not a common therapy for people with SCI is a tragedy in my view. If you, or someone you know, has suffered a SCI, I highly recommend you send this info to your/their doctor and pursue this as a possible option. It’s important to note that testosterone deficiency is common after SCI, and according to the U.S. Department of Veterans Affairs SCI unit:


These findings confirm both a substantial population of men with SCI and with testosterone deficiency, and a significant association between testosterone level and severity of SCI. Measuring serum total testosterone levels should be included in standard screenings for patients with SCI…”


I can say, a very common report of those who go on TRT is a big reduction in general aches and pains in my experience, and again, it makes perfect sense to me. The future treatment of SCI will be the of use various growth factors and other modalities (such as stem cell therapy) to re grow/re connect the spinal cord. That technology is much closer than people realize, but it seems the med/sci community very slow to pursue this area as quickly as they should. Obviously, this approach could be used to repair damaged nerves and other tissues far less challenging than repairing a severely damage or severed spinal cord.


Cont:


http://www.brinkzone.com/articles/testosterone-and-spinal-cord-injuires-sci/
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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