Sperm counts significantly declining in men from North America, Europe

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[/style][style=color:#333333]BACKGROUND

Reported declines in sperm counts remain controversial today and recent trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm count for fertility, morbidity and mortality.





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OBJECTIVE AND RATIONALE

To provide a systematic review and meta-regression analysis of recent trends in sperm counts as measured by sperm concentration (SC) and total sperm count (TSC), and their modification by fertility and geographic group.[/style][style=color:#333333]



“In this comprehensive meta-analysis, sperm counts whether measured by SC or TSC declined significantly among men from North America, Europe and Australia during 1973–2011, with a 50–60% decline among men unselected by fertility, with no evidence of a ‘leveling off' in recent years,” the authors concluded.

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[style=font-weight:bold;]Reference[/style]







  1. Levine H, Jørgensen N, Martino-Andrade A, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis. [style=font-style:italic;]Hum Reprod Update. 25 July 2017. https://doi.org/10.1093/humupd/dmx022[/style]
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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