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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
so what *are* the possible causes of late-onset secondary hypogonadism?
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<blockquote data-quote="DragonBits" data-source="post: 138114" data-attributes="member: 18023"><p>There is a global decline in testosterone and fertility, one would think it has to be environmental.</p><p></p><p><strong>Maybe better to pin point a date what it started to affect you Vs how old you were.</strong></p><p><strong></strong></p><p><strong>For me, 1993-1994,</strong> suddenly I was tired, in 1995 I got a TT test and it was 376 ng/ld.</p><p></p><p>So all males would have been affected around 1993-1996+. The younger you are, the earlier it would have started. If you were born in 1970, you would be 23-25 during those years. now 58. If environmental, it was probably here for a long time before it became widespread enough to affect the world and probably stayed in the environment a long time. It may be still here, or may be gone. Depending on where you lived you either got more or less of the toxin. </p><p></p><p>An example: Dioxins from PCB, widely produced between 1930-1984, PCB containing dioxin are still in limited production today.</p><p></p><p>--------------------------------------------------------------------------------------</p><p>The United States was the single largest producer with over 600,000 tonnes produced between 1930 and 1977. The European region follows with nearly 450,000 tonnes through 1984. It is unlikely that a full inventory of global PCB production will ever be accurately tallied, as there were factories in Poland, East Germany, and Austria that produced unknown amounts of PCBs</p><p></p><p>There is evidence that crash dieters that have been exposed to PCBs have an elevated risk of health complications. Stored PCBs in the adipose tissue becomes mobilized into the blood when individuals begin to crash diet.[51] PCBs have shown toxic and mutagenic effects by interfering with hormones in the body. PCBs, depending on the specific congener, have been shown to both inhibit and imitate estradiol, the main sex hormone in females. Imitation of the estrogen compound can feed estrogen-dependent breast cancer cells, and possibly cause other cancers, such as uterine or cervical. Inhibition of estradiol can lead to serious developmental problems for both males and females, including sexual, skeletal, and mental development issues.[citation needed][52] <strong>In a cross-sectional study, PCBs were found to be negatively associated with testosterone levels in adolescent boys</strong>.[53]</p><p></p><p><strong>High PCB levels in adults have been shown to result in reduced levels of the thyroid hormone <a href="https://en.wikipedia.org/wiki/Triiodothyronine" target="_blank">triiodothyronine</a>, which affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. It also resulted in reduced immunity and increased thyroid disorders </strong></p><p></p><p><a href="https://en.wikipedia.org/wiki/Polychlorinated_biphenyl#Production" target="_blank">Polychlorinated biphenyl - Wikipedia</a></p><p></p><p>This is only one example, environmentalists have identified the dioxin as one of the "Dirty Dozen"</p><p></p><p><u>Interesting topic, I would be fairly convinced that toxins in the environment may have caused a world wide decline in testosterone, but even if they pinpoint the cause it doesn't help any of us. We still need to deal with the consequences. </u></p></blockquote><p></p>
[QUOTE="DragonBits, post: 138114, member: 18023"] There is a global decline in testosterone and fertility, one would think it has to be environmental. [B]Maybe better to pin point a date what it started to affect you Vs how old you were. For me, 1993-1994,[/B] suddenly I was tired, in 1995 I got a TT test and it was 376 ng/ld. So all males would have been affected around 1993-1996+. The younger you are, the earlier it would have started. If you were born in 1970, you would be 23-25 during those years. now 58. If environmental, it was probably here for a long time before it became widespread enough to affect the world and probably stayed in the environment a long time. It may be still here, or may be gone. Depending on where you lived you either got more or less of the toxin. An example: Dioxins from PCB, widely produced between 1930-1984, PCB containing dioxin are still in limited production today. -------------------------------------------------------------------------------------- The United States was the single largest producer with over 600,000 tonnes produced between 1930 and 1977. The European region follows with nearly 450,000 tonnes through 1984. It is unlikely that a full inventory of global PCB production will ever be accurately tallied, as there were factories in Poland, East Germany, and Austria that produced unknown amounts of PCBs There is evidence that crash dieters that have been exposed to PCBs have an elevated risk of health complications. Stored PCBs in the adipose tissue becomes mobilized into the blood when individuals begin to crash diet.[51] PCBs have shown toxic and mutagenic effects by interfering with hormones in the body. PCBs, depending on the specific congener, have been shown to both inhibit and imitate estradiol, the main sex hormone in females. Imitation of the estrogen compound can feed estrogen-dependent breast cancer cells, and possibly cause other cancers, such as uterine or cervical. Inhibition of estradiol can lead to serious developmental problems for both males and females, including sexual, skeletal, and mental development issues.[citation needed][52] [B]In a cross-sectional study, PCBs were found to be negatively associated with testosterone levels in adolescent boys[/B].[53] [B]High PCB levels in adults have been shown to result in reduced levels of the thyroid hormone [URL='https://en.wikipedia.org/wiki/Triiodothyronine']triiodothyronine[/URL], which affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. It also resulted in reduced immunity and increased thyroid disorders [/B] [URL="https://en.wikipedia.org/wiki/Polychlorinated_biphenyl#Production"]Polychlorinated biphenyl - Wikipedia[/URL] This is only one example, environmentalists have identified the dioxin as one of the "Dirty Dozen" [U]Interesting topic, I would be fairly convinced that toxins in the environment may have caused a world wide decline in testosterone, but even if they pinpoint the cause it doesn't help any of us. We still need to deal with the consequences. [/U] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
so what *are* the possible causes of late-onset secondary hypogonadism?
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