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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
so what *are* the possible causes of late-onset secondary hypogonadism?
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<blockquote data-quote="Gman86" data-source="post: 137839" data-attributes="member: 15043"><p>So I’m obviously just speculating here, but I remember reading that the way the negative feedback loop works, is it starts with estrogen, not testosterone. So yes testosterone turns into estrogen obviously, but I remember reading that the body senses estrogen levels, and that’s how it figures out how much testosterone needs to be produced. It does this by telling the hypothalamus to make more, or less, Gonadotropin-releasing hormone (GnRH). GnRH then stimulates the anterior pituitary to release LH and FSH. The more GnRH that is sent to the anterior pituitary, the more LH and FSH are sent to the testicles. LH is responsible for activating the leydig cells in the testicles, which will then make testosterone, and FSH is more for reproductive purposes. </p><p></p><p>But the reason I say all this, is because if Estrogen is what starts this chain reaction, and testosterone is ultimately decreased, or increased, depending on the person’s estrogen level, maybe the body reacts to xenoestrogens in the environment, in our food, in products we use, blue light from electronic devices, etc., the same way it would react to actual estrogen. So say your estrogen isn’t that high, but you’re constantly getting bombarded with xenoestrogens. Maybe your body views this as having a high estrogen level. Your body will then think that since there’s a bunch of extra estrogen, there must be a bunch of extra testosterone, since estrogen aromatizes from testosterone. So to lower testosterone, your body will send the signal to lower GnRH, which will then lower your level of LH, and consequently lower your level of testosterone. </p><p></p><p>I most likely butchered that, but I think overall, the general idea could be what’s going on. Body see’s more estrogen in the body, in the form of xenoestrogens, it then lowers testosterone to try and decrease the estrogens in your body. I’m pretty sure the main mechanism your body uses to control estrogen levels is by manipulating testosterone levels. I could be wrong on that one though.</p></blockquote><p></p>
[QUOTE="Gman86, post: 137839, member: 15043"] So I’m obviously just speculating here, but I remember reading that the way the negative feedback loop works, is it starts with estrogen, not testosterone. So yes testosterone turns into estrogen obviously, but I remember reading that the body senses estrogen levels, and that’s how it figures out how much testosterone needs to be produced. It does this by telling the hypothalamus to make more, or less, Gonadotropin-releasing hormone (GnRH). GnRH then stimulates the anterior pituitary to release LH and FSH. The more GnRH that is sent to the anterior pituitary, the more LH and FSH are sent to the testicles. LH is responsible for activating the leydig cells in the testicles, which will then make testosterone, and FSH is more for reproductive purposes. But the reason I say all this, is because if Estrogen is what starts this chain reaction, and testosterone is ultimately decreased, or increased, depending on the person’s estrogen level, maybe the body reacts to xenoestrogens in the environment, in our food, in products we use, blue light from electronic devices, etc., the same way it would react to actual estrogen. So say your estrogen isn’t that high, but you’re constantly getting bombarded with xenoestrogens. Maybe your body views this as having a high estrogen level. Your body will then think that since there’s a bunch of extra estrogen, there must be a bunch of extra testosterone, since estrogen aromatizes from testosterone. So to lower testosterone, your body will send the signal to lower GnRH, which will then lower your level of LH, and consequently lower your level of testosterone. I most likely butchered that, but I think overall, the general idea could be what’s going on. Body see’s more estrogen in the body, in the form of xenoestrogens, it then lowers testosterone to try and decrease the estrogens in your body. I’m pretty sure the main mechanism your body uses to control estrogen levels is by manipulating testosterone levels. I could be wrong on that one though. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
so what *are* the possible causes of late-onset secondary hypogonadism?
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