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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Significant decrease in SHBG with the use of Oral TU (JATENZO)
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<blockquote data-quote="Wilson7" data-source="post: 221603" data-attributes="member: 39729"><p>In Bhasin's 2005 study of graded T dosing in older men there was no significant change in SHBG in dosing up to and including 600 mg/wk that resulted in a total T of 3286 ng/dl. If you compared the change in the means, while not significant there was a 15 - 25% decrease in SHBG with all dosing 25 - 600 mg/wk, lots of variability and no control comparison. No change in LFTs at any dose and a decrease in HDL only with the 600 mg/wk but not 300 mg/wk dosing. C-17 androgens and SARMs are notorious for crushing SHBG as well as HDL.</p></blockquote><p></p>
[QUOTE="Wilson7, post: 221603, member: 39729"] In Bhasin's 2005 study of graded T dosing in older men there was no significant change in SHBG in dosing up to and including 600 mg/wk that resulted in a total T of 3286 ng/dl. If you compared the change in the means, while not significant there was a 15 - 25% decrease in SHBG with all dosing 25 - 600 mg/wk, lots of variability and no control comparison. No change in LFTs at any dose and a decrease in HDL only with the 600 mg/wk but not 300 mg/wk dosing. C-17 androgens and SARMs are notorious for crushing SHBG as well as HDL. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Significant decrease in SHBG with the use of Oral TU (JATENZO)
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