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*T is subsequently bound to sex hormone-binding globulin (SHBG), a hepatic synthesized protein whose level is increased, in part, by hepatic conditions (e.g. fatty liver, non-alcoholic steatohepatitis, cirrhotic liver) and whose level is decreased, in part, by improvement in these hepatic conditions. 




Lower SHBG levels are associated with NAFLD (non-alcoholic fatty liver disease).


NASH (non-alcoholic steatohepatitis) and liver cirrhosis can increase SHBG.



[URL unfurl="true"]https://www.excelmale.com/forum/threads/present-clinical-data-on-oral-t-lpcn-1144-at-2022-nash-tag-conference.24684/[/URL]


*increase in Sex Hormone Binding Globulin (SHBG) is reported with the progression of NASH 


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