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The max hematocrit increase at high altitudes is about 4 percent.  Most men at high altitudes have hematocrits that do not reach levels over 52.  Extrapolating high altitude conditions to men on testosterone replacement whose hematocrit can climb to values over 60 is not justified at all.


High and Low Hematocrit Increase Cardiovascular Risks



Altitude adaptation through hematocrit changes.



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