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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Should I do TRT?
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<blockquote data-quote="Cataceous" data-source="post: 182786" data-attributes="member: 38109"><p>I don't think the concept of "quaternary hypogonadism" works. For elevated SHBG to be identified as a unique cause of hypogonadism it would need to be so high that other parts of the system are maxed out at reasonable physiological limits. For example, if the hypothalamus were at it's limit of GnRH production, or the pituitary were at its limit of LH production, and the hormone levels were either high in-range or over-range.</p><p></p><p>That's certainly not the case here, with LH being low in-range. And SHBG of 44 nMol/L is not excessive.</p><p></p><p>[USER=40782]@calmcalmcalm[/USER]: Low doses of mesterolone (Proviron) or ostarine are <a href="https://www.excelmale.com/forum/threads/are-guys-that-do-well-on-low-dose-clomid-unicorns-or-do-they-really-exist.6095/post-158209" target="_blank">mentioned</a> as possible ways to reduce SHBG without a lot of HPTA suppression, perhaps in conjunction with a SERM. You'd need to determine if these are legal where you are and find a doctor to supervise.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 182786, member: 38109"] I don't think the concept of "quaternary hypogonadism" works. For elevated SHBG to be identified as a unique cause of hypogonadism it would need to be so high that other parts of the system are maxed out at reasonable physiological limits. For example, if the hypothalamus were at it's limit of GnRH production, or the pituitary were at its limit of LH production, and the hormone levels were either high in-range or over-range. That's certainly not the case here, with LH being low in-range. And SHBG of 44 nMol/L is not excessive. [USER=40782]@calmcalmcalm[/USER]: Low doses of mesterolone (Proviron) or ostarine are [URL='https://www.excelmale.com/forum/threads/are-guys-that-do-well-on-low-dose-clomid-unicorns-or-do-they-really-exist.6095/post-158209']mentioned[/URL] as possible ways to reduce SHBG without a lot of HPTA suppression, perhaps in conjunction with a SERM. You'd need to determine if these are legal where you are and find a doctor to supervise. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Should I do TRT?
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