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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Shitty libido ed fatigue help me! Labs posted
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<blockquote data-quote="YBWV" data-source="post: 134867" data-attributes="member: 32335"><p>That's interesting that you're talking about the T:E2 ratio in your clinic as we've been discussing it again in the last few days here on Excelmale so your findings would add greatly to the discussion.</p><p></p><p>I note that T:E2 is used elsewhere in the diagnosis and management of various morbidities however my conjecture is that in the complaints that the OP of this thread raises (libido, ed, fatigue) T:E2 is actually a bit of a red herring. I believe that it's the DHT:E2 ratio that matters most.</p><p></p><p>In the modulation of sex hormones T:E2 could be seen as a sort of de facto measurement of DHT:E2 as if a patient reported relief of symptoms at a T:E2 ratio of 25:1, and had 5a-r conversion of 10% of TT, then DHT:T2 would be 2.5:1.</p><p></p><p>We know that DHT and E2, as 2 metabolites of T, have separate and vital roles in overall sexual function, so it would seem instructive to know what ratios might work best at adequate, physiological hormone levels.</p><p></p><p>My own n=1 experience is that I find great function with a a DHT:E2 ratio of between 3 and 4:1. Several other members have indicated similar findings. Of course far too few to be of any statistical use.</p><p></p><p>I can't find that it's an area that has been studied or even much mentioned so it would be great to know if any of the above correlates with your own clinical experience.</p></blockquote><p></p>
[QUOTE="YBWV, post: 134867, member: 32335"] That's interesting that you're talking about the T:E2 ratio in your clinic as we've been discussing it again in the last few days here on Excelmale so your findings would add greatly to the discussion. I note that T:E2 is used elsewhere in the diagnosis and management of various morbidities however my conjecture is that in the complaints that the OP of this thread raises (libido, ed, fatigue) T:E2 is actually a bit of a red herring. I believe that it's the DHT:E2 ratio that matters most. In the modulation of sex hormones T:E2 could be seen as a sort of de facto measurement of DHT:E2 as if a patient reported relief of symptoms at a T:E2 ratio of 25:1, and had 5a-r conversion of 10% of TT, then DHT:T2 would be 2.5:1. We know that DHT and E2, as 2 metabolites of T, have separate and vital roles in overall sexual function, so it would seem instructive to know what ratios might work best at adequate, physiological hormone levels. My own n=1 experience is that I find great function with a a DHT:E2 ratio of between 3 and 4:1. Several other members have indicated similar findings. Of course far too few to be of any statistical use. I can't find that it's an area that has been studied or even much mentioned so it would be great to know if any of the above correlates with your own clinical experience. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Shitty libido ed fatigue help me! Labs posted
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