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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
SHBG Levels
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<blockquote data-quote="AbsoluteZ3R0" data-source="post: 103283" data-attributes="member: 15174"><p>It's pretty much the opposite. Those with low SHBG will wind up with less total and free (contrary to popular belief) testosterone than those with normal levels of SHBG. Generally speaking, those with low SHBG will have a higher free to total testosterone ratio than those with mid-range SHBG, but the actual levels will tend to be lower on a mg per mg basis. Because SHBG binds more strongly to androgens than estrogens, those with low SHBG are also more sensitive to estradiol, because they will have an augmented free/total ratio of e2 compared to someone with mid-range SHBG levels. This ratio will be even more accented than the free t/total t ratio. On the other hand, those with too high SHBG will have disproportionately high total testosterone levels relative to free testosterone.</p></blockquote><p></p>
[QUOTE="AbsoluteZ3R0, post: 103283, member: 15174"] It's pretty much the opposite. Those with low SHBG will wind up with less total and free (contrary to popular belief) testosterone than those with normal levels of SHBG. Generally speaking, those with low SHBG will have a higher free to total testosterone ratio than those with mid-range SHBG, but the actual levels will tend to be lower on a mg per mg basis. Because SHBG binds more strongly to androgens than estrogens, those with low SHBG are also more sensitive to estradiol, because they will have an augmented free/total ratio of e2 compared to someone with mid-range SHBG levels. This ratio will be even more accented than the free t/total t ratio. On the other hand, those with too high SHBG will have disproportionately high total testosterone levels relative to free testosterone. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
SHBG Levels
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