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From what I've read, there are a few things this doc did wrong:


1. Prescribed Clomid instead of Enclomiphine

2. Started at 25mg ED out of the gate; seems like 12.5mg is a better place to start, and possibly not even every day.

3. Two 1mg doses of Anastrozole per week is extremely high. He also did not take baseline estrodial levels to determine what my "normal" was before treatment.


While I don't have any labs to back it up, yes, my hunch is that the high dose Anastrozole was crashing e2, leading to the panic attacks and anxiety. While my T numbers were up along with strength and recovery, my mood was not great on treatment. I think this is because we were crashing e2 twice a week, rather than managing it to a healthy level. I say this because I took it upon myself to ditch the Anastrozole for a week after doing some research, then tried a half dose (0.5mg, still too high) and promptly had the best day of my entire treatment period. Confidence, quick thinking, good libido, strength, recovery; everything. That was how I expected TRT to feel, it was just never dialed in correctly.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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