scrotum application questions

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ta406

Member
I have recently switched from injections to a 20% lipoderm based cream. My FT stayed the same as injections, which was 23. The strange thing was that my TT dropped from 1500+ on injections to 1050 with the cream. I think this is probably a good thing. My question is that the twice a day scrotal application was kind a pain. I typically shower at night and apply the first application. When I wake up in the morning and apply the cream again, it doesn't seem like it absorbs as well, and my scrotum feels sticky all day. I have tried washing my balls first then applying the cream, which works but its a royal pain. Recently, I have started to apply one pump to my forearms and the other to my scrotum at night. I'm sure the absorption rate went down even though my forearms are fairly lean and have visible veins. Just curious what others have been doing.
 
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madman

Super Moderator
I have recently switched from injections to a 20% lipoderm based cream. My FT stayed the same as injections, which was 23. The strange thing was that my TT dropped from 1500+ on injections to 1050 with the cream. I think this is probably a good thing. My question is that the twice a day scrotal application was kind a pain. I typically shower at night and apply the first application. When I wake up in the morning and apply the cream again, it doesn't seem like it absorbs as well, and my scrotum feels sticky all day. I have tried washing my balls first then applying the cream, which works but its a royal pain. Recently, I have started to apply one pump to my forearms and the other to my scrotum at night. I'm sure the absorption rate went down even though my forearms are fairly lean and have visible veins. Just curious what others have been doing.

What is the main reason you switched from injections to cream (scrotal application)?
 

ta406

Member
Ive been on TRT for a few years now and have been suffering form low libido and ED. Low dose cialis and viagra take care of the ED but I would love to get my libido back. I've tried injections ranging from every day, to every 3.5 days at varying dosages, HCG, no HCG, arimidex, no arimidex. Nothing seems to matter. Every time I would change up my protocol, I would give it a minimum of 6 weeks then get blood work done. I figured I would give a compounded cream a try since nothing has really worked. I'm 5'9, a lean 200 pounds, eat well exercise regularly and by all accounts in good health.
 

S1W

Well-Known Member
I started out on a 20% cream protocol. Spent about 4 months on it and felt like it was a pretty good protocol. For various reasons switched to injections.

I started out with scrotal application then switched to wrist/forearms and sometimes inner thighs, only rubbing any excess cream residue on scrotum. Alternate sides with each application. Apparently different sites affect absorption rates somewhat, but I never noticed. This worked well for me. Also, I wore a nitrile glove to rub it in and avoid wasting cream.

Good luck and if you wouldn’t mind, please consider updating this thread in a month or two and let us know how things are going for you.
 

stx359

Active Member
I recently added 20% cream to my TRT regimen after consulting with Dr. Crisler. I have been on TRT/HCG for almost a year and a half and have textbook numbers, TT-1000, FT-25, everything else in range, but my libido still wasn't where I wanted it. My erectile function was adequate but not ideal and intimacy was not as gratifying as it once was. I also use the NO stack including 5 mg Cialis morning and evening. I added one pump a day of 20% cream to the scrotum without adjusting my injectable dose which is 80 mg twice a week. I will run labs after one month. I have been on the cream for two weeks. Dr. Crisler said to draw blood two hours after application. I have to say that of all the things I have tried since beginning TRT 18 months ago this has had the greatest benefit. I have been very pleased with a discernible increase in libido and as a result better erectile function and more natural and spontaneous intimacy with my wife who has been extremely pleased with the change. I often wonder if my less than ideal erectile function was due more to libido than anything else as I am in top shape with normal BP and cholesterol and no medical reason for ED.

It is yet to be seen if the results will persist and I anticipate needing to lower my injectable dose after I draw blood in two weeks. Also I have dealt with terrible back acne and am carefully watching to see if the increase in DHT makes that reappear. Being the curious sort I am also wondering if a second application in the evening or two pumps in the morning with an additional reduction in the injected dose will result in additional benefits but those are questions I will defer to Dr. C on. it bears mentioning that NO ONE would agree to let me do injectable and topical testosterone concurrently and he seemed to think it was a perfectly reasonable choice.
 

eli

Active Member
Ive been on TRT for a few years now and have been suffering form low libido and ED. Low dose cialis and viagra take care of the ED but I would love to get my libido back. I've tried injections ranging from every day, to every 3.5 days at varying dosages, HCG, no HCG, arimidex, no arimidex. Nothing seems to matter. Every time I would change up my protocol, I would give it a minimum of 6 weeks then get blood work done. I figured I would give a compounded cream a try since nothing has really worked. I'm 5'9, a lean 200 pounds, eat well exercise regularly and by all accounts in good health.

Are you a low shbg patient?
 

ta406

Member
I recently added 20% cream to my TRT regimen after consulting with Dr. Crisler. I have been on TRT/HCG for almost a year and a half and have textbook numbers, TT-1000, FT-25, everything else in range, but my libido still wasn't where I wanted it. My erectile function was adequate but not ideal and intimacy was not as gratifying as it once was. I also use the NO stack including 5 mg Cialis morning and evening. I added one pump a day of 20% cream to the scrotum without adjusting my injectable dose which is 80 mg twice a week. I will run labs after one month. I have been on the cream for two weeks. Dr. Crisler said to draw blood two hours after application. I have to say that of all the things I have tried since beginning TRT 18 months ago this has had the greatest benefit. I have been very pleased with a discernible increase in libido and as a result better erectile function and more natural and spontaneous intimacy with my wife who has been extremely pleased with the change. I often wonder if my less than ideal erectile function was due more to libido than anything else as I am in top shape with normal BP and cholesterol and no medical reason for ED.

It is yet to be seen if the results will persist and I anticipate needing to lower my injectable dose after I draw blood in two weeks. Also I have dealt with terrible back acne and am carefully watching to see if the increase in DHT makes that reappear. Being the curious sort I am also wondering if a second application in the evening or two pumps in the morning with an additional reduction in the injected dose will result in additional benefits but those are questions I will defer to Dr. C on. it bears mentioning that NO ONE would agree to let me do injectable and topical testosterone concurrently and he seemed to think it was a perfectly reasonable choice.

I'm actually thinking about doing the same thing. Add injections back in along with my cream. I was slightly overprescribed when I was on injections so I have stockpiled enough for a little experimentation. I haven't decided what my dosage will be with either the cream or my test cypionate. I probably felt best at 60mg test c 2x a week. I'm thinking about slowly increasing my free test to see if it gives me any improvements. I will have to monitor my hematocrit because it did have a tendency to rise when my TT climbed above 1500.

80mg 2x a week plus a pump or 2 of 20% is a pretty stout dose. I'd be curious to know what your SHBG is and what your results are. Also, are you using and AI and what is your HCG protocol?
 
I use cream and injections but the cream is biased to DHT treatment and no necessarily an addition to my injections, per se. Works very well, 2 hours later my DHT is up to or just over the lab range when I run at about ~40 on a 16-79 scale, untreated.
Ive been using it PRN and not daily, but I have applied 25mg about 1-2hours before date time and i do think I get something libido etc from using it that way.
 

DragonBits

Well-Known Member
I use cream and injections but the cream is biased to DHT treatment and no necessarily an addition to my injections, per se. Works very well, 2 hours later my DHT is up to or just over the lab range when I run at about ~40 on a 16-79 scale, untreated.
Ive been using it PRN and not daily, but I have applied 25mg about 1-2hours before date time and i do think I get something libido etc from using it that way.

I think it's safer to keep DHT in the middle of the range, IE: 50-75 ng/dL Though free DHT is determined by shbg. I don't think many ever measure Free DHT, I never have.

What does the research say about androgen use and cerebrovascular events?

Too high or too low DHT has been associated with an increased risk of stroke.

Experiment all you want, I also have experimented with testosterone injections (Nebido) while adding HCG, DHEA, testosterone cream including scrotal application, I didn't see any benefit and my PSA score went up. PSA never went up before while on TRT/Nebido only for 5 years.

BTW, when I did see an increase in libido when on Nebido only, it wasn't like I had to "think" about did my libido increase ?, I was getting erections every random thought of sex or look from a woman, I had sex 4-5 times in one day. It was fun at times, but annoying after a while. However, I have no idea of what my E2, DHEA, DHT levels were at the time, only that I didn't do anything outside of Nebido.
 

stx359

Active Member
I'm actually thinking about doing the same thing. Add injections back in along with my cream. I was slightly overprescribed when I was on injections so I have stockpiled enough for a little experimentation. I haven't decided what my dosage will be with either the cream or my test cypionate. I probably felt best at 60mg test c 2x a week. I'm thinking about slowly increasing my free test to see if it gives me any improvements. I will have to monitor my hematocrit because it did have a tendency to rise when my TT climbed above 1500.

80mg 2x a week plus a pump or 2 of 20% is a pretty stout dose. I'd be curious to know what your SHBG is and what your results are. Also, are you using and AI and what is your HCG protocol?

My SHBG has always been in the mid 40's so rather high. I use 150 IU of HCG daily. My last sensitive E2 was 37 but it has run into the 40's before as well, though I have never had any E2 symptoms but I have convinced myself in the past that my lower libido was E2 related - I even procured an Rx for an AI which still sits on my shelf untouched. I ran a free E2 first and discovered that it was right in range not high. I am pretty sure the AI would have crashed my normal free E2. From reading this blog I think AIs are the most overused and abused meds on here.
 
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