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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Scrotal Cream absorption in relation to dosage applied - seems high
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<blockquote data-quote="Cataceous" data-source="post: 143709" data-attributes="member: 38109"><p>It may be a case of diminishing returns; huge doses like that reduce the efficiency of the limited skin area. <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12357" target="_blank">This paper</a> found about an "eightfold increase in testosterone bioavailability, using the scrotal compared with abdominal skin routes." But the comparison was made with 12.5 mg applied to the scrotal skin. Other doses tested were 25 mg and 50 mg. The dose-response curves demonstrate the decreasing returns, with the response at 50 mg mostly less than double the response at 12.5 mg.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 143709, member: 38109"] It may be a case of diminishing returns; huge doses like that reduce the efficiency of the limited skin area. [URL='https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12357']This paper[/URL] found about an "eightfold increase in testosterone bioavailability, using the scrotal compared with abdominal skin routes." But the comparison was made with 12.5 mg applied to the scrotal skin. Other doses tested were 25 mg and 50 mg. The dose-response curves demonstrate the decreasing returns, with the response at 50 mg mostly less than double the response at 12.5 mg. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Scrotal Cream absorption in relation to dosage applied - seems high
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