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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
SARMs versus AAS: Different Side Effects?
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<blockquote data-quote="madman" data-source="post: 190775" data-attributes="member: 13851"><p><strong>Figure 2. <span style="color: rgb(184, 49, 47)">The potential impacts of varying SARMs on the male hypothalamic-pituitary-gonadal axis.</span> <span style="color: rgb(44, 130, 201)"><u>Amongst those most comprehensively researched and commercially available compounds with regards to these effects </u></span><span style="color: rgb(0, 0, 0)"><u>(gonadotropins and testosterone outcomes)</u></span><span style="color: rgb(44, 130, 201)"><u> are enobosarm, LGD-4033, and S-4. Each display widely varying effects on the axis along with the entire feedback system, along with wholly underresearched downstream impacts on systemic physiology</u>. </span><span style="color: rgb(26, 188, 156)">Mechanisms of each SARM and the drug class, in general, are unclear but may be sourced in dose-dependent effects and/or the potential for specific receptor-mediated antagonism. <u>We also posit the putatively deleterious impacts of attenuated androgen and subsequent estradiol following high-dose and/or chronic SARM use</u>. </span></strong></p><p>[ATTACH=full]11628[/ATTACH]</p><p><strong><span style="color: rgb(26, 188, 156)">FSH</span> = follicle-stimulating hormone; <span style="color: rgb(26, 188, 156)">GnRH</span> = gonadotropin releasing hormone, <span style="color: rgb(26, 188, 156)">LH</span> = luteinizing hormone </strong></p></blockquote><p></p>
[QUOTE="madman, post: 190775, member: 13851"] [B]Figure 2. [COLOR=rgb(184, 49, 47)]The potential impacts of varying SARMs on the male hypothalamic-pituitary-gonadal axis.[/COLOR] [COLOR=rgb(44, 130, 201)][U]Amongst those most comprehensively researched and commercially available compounds with regards to these effects [/U][/COLOR][COLOR=rgb(0, 0, 0)][U](gonadotropins and testosterone outcomes)[/U][/COLOR][COLOR=rgb(44, 130, 201)][U] are enobosarm, LGD-4033, and S-4. Each display widely varying effects on the axis along with the entire feedback system, along with wholly underresearched downstream impacts on systemic physiology[/U]. [/COLOR][COLOR=rgb(26, 188, 156)]Mechanisms of each SARM and the drug class, in general, are unclear but may be sourced in dose-dependent effects and/or the potential for specific receptor-mediated antagonism. [U]We also posit the putatively deleterious impacts of attenuated androgen and subsequent estradiol following high-dose and/or chronic SARM use[/U]. [/COLOR][/B] [ATTACH type="full"]11628[/ATTACH] [B][COLOR=rgb(26, 188, 156)]FSH[/COLOR] = follicle-stimulating hormone; [COLOR=rgb(26, 188, 156)]GnRH[/COLOR] = gonadotropin releasing hormone, [COLOR=rgb(26, 188, 156)]LH[/COLOR] = luteinizing hormone [/B] [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
SARMs versus AAS: Different Side Effects?
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