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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Risk of Transference with cream
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<blockquote data-quote="madman" data-source="post: 211746" data-attributes="member: 13851"><p>Should dry fairly quickly once spread/gently rubbed.</p><p></p><p>Even then after absorption, there will always be some left on the skin surface.</p><p></p><p>If you are concerned with transfer then your best bet would be to wash off the area/cover-up.</p><p></p><p><em><strong>*The risk of transfer is <u>substantially reduced</u> by wearing clothes covering the application area. The <u>majority of residual testosterone</u> is removed from the skin surface by washing with soap and water prior to contact</strong></em></p><p></p><p></p><p></p><p></p><p><strong><em>*When transdermal testosterone gel or cream is applied to the upper body <u>9-14% is absorbed</u> (2). <u>The rest remains on the skin surface and there is the potential risk of passive transfer to partners and children</u>. This is why the Consumer Medicine Information leaflets in all transdermal products advise covering the areas of application with clothing to minimize the risk.</em></strong></p><p></p><p><em><strong>*Scrotal application negates this risk and results in up to an <u>8-fold increase in testosterone bioavailability</u>, using the scrotal compared to the abdominal skin routes. (3)</strong></em></p><p></p><p></p><p></p><p></p><p></p><p><strong><u>Potential for transfer</u> (gel/cream)</strong></p><p></p><p><em>Transdermal testosterone cream can be transferred to other persons by close skin-to-skin contact, resulting in increased testosterone serum levels and, with repeated contact, possible adverse effects. <strong>In women, this may cause the growth of facial and/or body hair, deepening of the voice, irregularities of the menstrual cycle; in children, this may cause premature puberty and genital enlargement, in case of repeat contact (inadvertent androgenization).</strong> If virilization occurs, testosterone therapy should be promptly discontinued until the cause has been identified.</em></p><p><em></em></p><p><em><strong>The physician should inform the patient carefully about the risk of testosterone transfer and about safety instructions (see below).</strong> ANDROFORTE 5 should not be prescribed to patients with a major risk of non-compliance with safety instructions (e.g. severe alcoholism, drug abuse, and severe psychiatric disorders).</em></p><p><em></em></p><p><em><strong>The risk of transfer is <u>substantially reduced</u> by wearing clothes covering the application area. The <u>majority of residual testosterone</u> is removed from the skin surface by washing with soap and water prior to contact.</strong></em></p><p></p><p><strong>As a result, the following precautions are recommended: </strong></p><p><strong></strong></p><p><strong>For the patient:</strong></p><p></p><p>• Wash hands thoroughly with soap and water after applying the cream.</p><p></p><p>• Cover the application area with clothing once the cream has dried.</p><p></p><p>• Wash before any situation in which skin-to-skin contact is foreseen.</p><p></p><p></p><p><strong>For people not being treated with ANDROFORTE 5: </strong></p><p></p><p>• In the event of contact with an application area that has not been washed or is not covered with clothing wash the area of skin onto which testosterone may have been transferred as soon as possible, using soap and water.</p><p></p><p>• Report the development of signs of excessive androgen exposure such as acne or hair modification.</p><p></p><p></p><p><strong><em>*To improve partner safety the patient should be advised to wear a T-shirt covering the upper body application site during the contact period or to shower before sexual intercourse.</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*To improve partner safety using scrotal application wash the genital area with a damp warm flannel before sexual intercourse.</em></strong></p><p></p><p><em><strong>*Furthermore, it is recommended to wear clothing covering the upper body application site during contact periods with children in order to avoid transference to children.</strong></em></p><p><em><strong></strong></em></p><p><em><strong>*Pregnant women must avoid any contact with ANDROFORTE 5 application sites. In the case of pregnancy of the partner, the patient must be particularly careful to avoid the potential transfer.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 211746, member: 13851"] Should dry fairly quickly once spread/gently rubbed. Even then after absorption, there will always be some left on the skin surface. If you are concerned with transfer then your best bet would be to wash off the area/cover-up. [I][B]*The risk of transfer is [U]substantially reduced[/U] by wearing clothes covering the application area. The [U]majority of residual testosterone[/U] is removed from the skin surface by washing with soap and water prior to contact[/B][/I] [B][I]*When transdermal testosterone gel or cream is applied to the upper body [U]9-14% is absorbed[/U] (2). [U]The rest remains on the skin surface and there is the potential risk of passive transfer to partners and children[/U]. This is why the Consumer Medicine Information leaflets in all transdermal products advise covering the areas of application with clothing to minimize the risk.[/I][/B] [I][B]*Scrotal application negates this risk and results in up to an [U]8-fold increase in testosterone bioavailability[/U], using the scrotal compared to the abdominal skin routes. (3)[/B][/I] [B][U]Potential for transfer[/U] (gel/cream)[/B] [I]Transdermal testosterone cream can be transferred to other persons by close skin-to-skin contact, resulting in increased testosterone serum levels and, with repeated contact, possible adverse effects. [B]In women, this may cause the growth of facial and/or body hair, deepening of the voice, irregularities of the menstrual cycle; in children, this may cause premature puberty and genital enlargement, in case of repeat contact (inadvertent androgenization).[/B] If virilization occurs, testosterone therapy should be promptly discontinued until the cause has been identified. [B]The physician should inform the patient carefully about the risk of testosterone transfer and about safety instructions (see below).[/B] ANDROFORTE 5 should not be prescribed to patients with a major risk of non-compliance with safety instructions (e.g. severe alcoholism, drug abuse, and severe psychiatric disorders). [B]The risk of transfer is [U]substantially reduced[/U] by wearing clothes covering the application area. The [U]majority of residual testosterone[/U] is removed from the skin surface by washing with soap and water prior to contact.[/B][/I] [B]As a result, the following precautions are recommended: For the patient:[/B] • Wash hands thoroughly with soap and water after applying the cream. • Cover the application area with clothing once the cream has dried. • Wash before any situation in which skin-to-skin contact is foreseen. [B]For people not being treated with ANDROFORTE 5: [/B] • In the event of contact with an application area that has not been washed or is not covered with clothing wash the area of skin onto which testosterone may have been transferred as soon as possible, using soap and water. • Report the development of signs of excessive androgen exposure such as acne or hair modification. [B][I]*To improve partner safety the patient should be advised to wear a T-shirt covering the upper body application site during the contact period or to shower before sexual intercourse. *To improve partner safety using scrotal application wash the genital area with a damp warm flannel before sexual intercourse.[/I][/B] [I][B]*Furthermore, it is recommended to wear clothing covering the upper body application site during contact periods with children in order to avoid transference to children. *Pregnant women must avoid any contact with ANDROFORTE 5 application sites. In the case of pregnancy of the partner, the patient must be particularly careful to avoid the potential transfer.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Risk of Transference with cream
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