Review: Plant-Based Estrogen Effects Still Not Understood

Nelson Vergel

Founder, ExcelMale.com
"... there are areas where phytoestrogens do show promise, the team emphasized. For example, in breast cancer, a 2013 analysis of 40 randomized controlled trials, 11 uncontrolled trials, and 80 observational studies led to the conclusion that soy consumption may be associated with reduced risk of breast cancer incidence, recurrence, and mortality.Even in this case, however, the authors indicated that there is not enough evidence to confirm the safety of using soy isoflavones in doses that are high enough (generally >100 mg/day) to obtain the anti-cancer benefits.

Conversely, some of the more widely discussed harmful effects of phytoestrogens also remain unproven. Rietjens and colleagues highlighted a 1997 study in which the soy isoflavones daidzein and genistein were found to inhibit thyroid peroxidase, but no other adverse effects on thyroid functions had been observed.

Human trials on soy isoflavones and thyroid function are entirely inconclusive, Rietjens and colleagues found."

http://www.medpagetoday.com/Endocri...id=nl_mpt_DHE_2016-10-15&eun=g777076d0r&pos=0
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
5
Guests online
321
Total visitors
326

Latest posts

Back
Top