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5mcg twice a day is the dose. From my understanding T3 effects last longer than 6 hrs. You divide the dose to keep from spiking it up causing side effects. Taking 10mcg at one time is not the same as dividing it. Kind of like dosing T into more smaller doses instead of one big one. Pfizer says dose once a day. http://labeling.pfizer.com/ShowLabeling.aspx?id=703
