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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Regulatory Role of Sex Hormones in Cardiovascular Calcification
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<blockquote data-quote="madman" data-source="post: 200118" data-attributes="member: 13851"><p><strong>Figure 3.</strong> <strong>Estrogen binds to estrogen receptors (ERs), which act as transcription factors to regulate the expression of genes containing estrogen response elements (ERE). In addition, estrogen also rapidly induces phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling through the orphan G-protein coupled receptor (GPR30). Through genomic and non-genomic pathways, estrogen regulates a wide range of vascular cell functions, including proliferation, migration, and senescence. E2- Estradiol. Testosterone acts in a similar mechanism, binding to the androgen receptor (AR), which acts as transcription factors to regulate the expression of genes containing the androgen response elements (ARE). Testosterone is also believed to have non-genomic effects, although these pathways are less clear than estrogens.</strong></p><p><strong>[ATTACH=full]13860[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 200118, member: 13851"] [B]Figure 3.[/B] [B]Estrogen binds to estrogen receptors (ERs), which act as transcription factors to regulate the expression of genes containing estrogen response elements (ERE). In addition, estrogen also rapidly induces phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling through the orphan G-protein coupled receptor (GPR30). Through genomic and non-genomic pathways, estrogen regulates a wide range of vascular cell functions, including proliferation, migration, and senescence. E2- Estradiol. Testosterone acts in a similar mechanism, binding to the androgen receptor (AR), which acts as transcription factors to regulate the expression of genes containing the androgen response elements (ARE). Testosterone is also believed to have non-genomic effects, although these pathways are less clear than estrogens. [ATTACH type="full"]13860[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Regulatory Role of Sex Hormones in Cardiovascular Calcification
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