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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Regarding my most recent Peptide therapy
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<blockquote data-quote="Jasen Bruce" data-source="post: 22374" data-attributes="member: 14"><p>Gene provided great feedback from a patient's perspective and highlighted the importance of diet/exercise. I personally also did not see physical changes until between 6-12 months. I did notice improved sleep and intense dreams soon after starting. I took 1000mcg daily for roughly 12 months, then 500mcg daily for a while, and now I maintain with 2-3 injections per week at 1000mcg. You wont see much literature on this yet, but Sermorelin can have an ongoing effect once levels are established within the pituitary. In one observational study we did at the pharmacy with Dr Walker, we took a physician who had been using 1000mcg of Sermorelin daily for a period of time and tracked his levels at baseline, and throughout treatment. IGF-1 remained elevated above baseline and within treatment range for 2 weeks after the last injection before starting to fall again. Once Sermorelin has optimized pituitary reserve of GH I assume the body can maintain while using up these reserves therefore the ongoing effect and why one can decrease injection frequency over time. </p><p></p><p>Not to be any more confusing, but we have recently learned that IGF-1 should not be the only test measured when using GHRH peptides. A double or triple specimen GH test will determine your response to the peptide by proving that your pituitary is responsive to GHRH and also showing the increase of GH from baseline after an injection.</p></blockquote><p></p>
[QUOTE="Jasen Bruce, post: 22374, member: 14"] Gene provided great feedback from a patient's perspective and highlighted the importance of diet/exercise. I personally also did not see physical changes until between 6-12 months. I did notice improved sleep and intense dreams soon after starting. I took 1000mcg daily for roughly 12 months, then 500mcg daily for a while, and now I maintain with 2-3 injections per week at 1000mcg. You wont see much literature on this yet, but Sermorelin can have an ongoing effect once levels are established within the pituitary. In one observational study we did at the pharmacy with Dr Walker, we took a physician who had been using 1000mcg of Sermorelin daily for a period of time and tracked his levels at baseline, and throughout treatment. IGF-1 remained elevated above baseline and within treatment range for 2 weeks after the last injection before starting to fall again. Once Sermorelin has optimized pituitary reserve of GH I assume the body can maintain while using up these reserves therefore the ongoing effect and why one can decrease injection frequency over time. Not to be any more confusing, but we have recently learned that IGF-1 should not be the only test measured when using GHRH peptides. A double or triple specimen GH test will determine your response to the peptide by proving that your pituitary is responsive to GHRH and also showing the increase of GH from baseline after an injection. [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Regarding my most recent Peptide therapy
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