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Hi all, hoping someone can help me with my most recent blood work results. My current protocol is 125mg per week of TestE split into two weekly doses (Mon, Thurs), followed by 0.25mg Anastrozole 24 hours after injection. Also on 50mcg of Thyroxine daily.

Results: (ref range)
Total T: 911 ng/dl (332-923)
E2: <13.6 pg/mL (<43.5)
TSH: 0.07 mIU/L (0.40-3.50)
FT4: 13.6 pmol/L (9.0-19.0)
FT3: 3.8 pmol/L (2.6-6.0)
Progesterone: <0.5 nmol/L (<4.1)

So obviously my E2 is a little low, and I've always been paranoid since going through pubertal gyno. What are peoples thoughts on my current protocol and results, should I be cutting down my AI dose, and if so, to what? Potentially to 0.375/week or to 0.25/week?
And with the thyroid results, is low TSH ok, so long as FT4/FT3 are in range?

Thanks in advance.

<blockquote data-quote="shady1991" data-source="post: 46300" data-attributes="member: 13745">Hi all, hoping someone can help me with my most recent blood work results. My current protocol is 125mg per week of TestE split into two weekly doses (Mon, Thurs), followed by 0.25mg Anastrozole 24 hours after injection. Also on 50mcg of Thyroxine daily.Results: (ref range)Total T: 911 ng/dl (332-923)E2: &lt;13.6 pg/mL (&lt;43.5)TSH: 0.07 mIU/L (0.40-3.50)FT4: 13.6 pmol/L (9.0-19.0)FT3: 3.8 pmol/L (2.6-6.0)Progesterone: &lt;0.5 nmol/L (&lt;4.1)So obviously my E2 is a little low, and I&#039;ve always been paranoid since going through pubertal gyno. What are peoples thoughts on my current protocol and results, should I be cutting down my AI dose, and if so, to what? Potentially to 0.375/week or to 0.25/week?And with the thyroid results, is low TSH ok, so long as FT4/FT3 are in range?Thanks in advance.</blockquote>

[QUOTE="shady1991, post: 46300, member: 13745"] Hi all, hoping someone can help me with my most recent blood work results. My current protocol is 125mg per week of TestE split into two weekly doses (Mon, Thurs), followed by 0.25mg Anastrozole 24 hours after injection. Also on 50mcg of Thyroxine daily. [B]Results: (ref range)[/B] [I]Total T:[/I] 911 ng/dl (332-923) [I]E2: [/I]<13.6 pg/mL (<43.5)[I] TSH: 0.07 [/I]mIU/L (0.40-3.50)[I] FT4: [/I]13.6 pmol/L (9.0-19.0) FT3: 3.8 pmol/L (2.6-6.0) Progesterone: <0.5 nmol/L (<4.1) So obviously my E2 is a little low, and I've always been paranoid since going through pubertal gyno. What are peoples thoughts on my current protocol and results, should I be cutting down my AI dose, and if so, to what? Potentially to 0.375/week or to 0.25/week? And with the thyroid results, is low TSH ok, so long as FT4/FT3 are in range? Thanks in advance. [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038