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Welcome to Excel Male and I wish you great success on your new protocol. Assumedly you mean 25mg (not .25mg). At 75mg per week it seems a bit low as a starting dose with the "typical" starting point being around 100mg per week. There are members here with a heck of a lot of experience and hopefully one will chime in but in the meantime I just wanted to say, I wouldn't take the Arimidex until/unless you have labs and symptoms that indicate you need it. Unwarranted Adex use has caused a lot of grief for many people starting TRT, myself included.