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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Question regarding allergic reaction after injecting Sermorelin
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<blockquote data-quote="Vince" data-source="post: 16785" data-attributes="member: 843"><p>Jasen Hi, I thought the question was interesting, I don't know if this information is of any use?</p><p></p><p>A large proportion of patients develop <a href="http://www.excelmale.com/script/main/art.asp?articlekey=25282" target="_blank">anti-</a> GRF antibodies at least once during treatment with Sermorelin. The significance of these antibodies is not clear and often a positive test at one growth assessment will become negative by the next assessment. The presence of antibodies does not appear to affect growth or appear to be related to a specific <a href="http://www.excelmale.com/script/main/art.asp?articlekey=26227" target="_blank">adverse reaction</a> profile. No generalized allergic reactions to Sermorelin have been reported.The most common treatment-related <a href="http://www.excelmale.com/script/main/art.asp?articlekey=2159" target="_blank">adverse event</a> (occurring in about 1 patient in 6) is local injection reaction characterized by <a href="http://www.excelmale.com/script/main/art.asp?articlekey=4723" target="_blank">pain</a>, swelling or redness. Of 350 patients exposed to Sermorelin in <a href="http://www.excelmale.com/script/main/art.asp?articlekey=2752" target="_blank">clinical trials</a>, three discontinued <a href="http://www.excelmale.com/script/main/art.asp?articlekey=10897" target="_blank">therapy</a> due to injection reactions. Other treatment-related adverse events had individual occurrence rates of less than 1% and include: headache, flushing, <a href="http://www.excelmale.com/script/main/art.asp?articlekey=11185" target="_blank">dysphagia</a>, dizziness, <a href="http://www.excelmale.com/script/main/art.asp?articlekey=11508" target="_blank">hyperactivity</a>, <a href="http://www.excelmale.com/script/main/art.asp?articlekey=13097" target="_blank">somnolence</a> and <a href="http://www.excelmale.com/script/main/art.asp?articlekey=5919" target="_blank">urticaria</a>.</p><p>When administered intravenously for diagnostic use, the following adverse reactions have been noted: flushing of the face, injection site pain, redness and/or swelling, <a href="http://www.excelmale.com/script/main/art.asp?articlekey=4510" target="_blank">nausea</a>, headache, vomiting, dysgeusia, pallor and tightness in the <a href="http://www.excelmale.com/script/main/art.asp?articlekey=19270" target="_blank">chest</a>.</p><p>[h=4]Drug Abuse and Dependence[/b] The clinical pharmacology suggests that Sermorelin is very unlikely to be associated with drug abuse or dependence and there have been no reports of this from clinical trials.</p><p><a href="http://www.rxlist.com/sermorelin-acetate-drug/side-effects-interactions.htm" target="_blank">http://www.rxlist.com/sermorelin-acetate-drug/side-effects-interactions.htm</a></p></blockquote><p></p>
[QUOTE="Vince, post: 16785, member: 843"] Jasen Hi, I thought the question was interesting, I don't know if this information is of any use? A large proportion of patients develop [URL="http://www.excelmale.com/script/main/art.asp?articlekey=25282"]anti-[/URL] GRF antibodies at least once during treatment with Sermorelin. The significance of these antibodies is not clear and often a positive test at one growth assessment will become negative by the next assessment. The presence of antibodies does not appear to affect growth or appear to be related to a specific [URL="http://www.excelmale.com/script/main/art.asp?articlekey=26227"]adverse reaction[/URL] profile. No generalized allergic reactions to Sermorelin have been reported.The most common treatment-related [URL="http://www.excelmale.com/script/main/art.asp?articlekey=2159"]adverse event[/URL] (occurring in about 1 patient in 6) is local injection reaction characterized by [URL="http://www.excelmale.com/script/main/art.asp?articlekey=4723"]pain[/URL], swelling or redness. Of 350 patients exposed to Sermorelin in [URL="http://www.excelmale.com/script/main/art.asp?articlekey=2752"]clinical trials[/URL], three discontinued [URL="http://www.excelmale.com/script/main/art.asp?articlekey=10897"]therapy[/URL] due to injection reactions. Other treatment-related adverse events had individual occurrence rates of less than 1% and include: headache, flushing, [URL="http://www.excelmale.com/script/main/art.asp?articlekey=11185"]dysphagia[/URL], dizziness, [URL="http://www.excelmale.com/script/main/art.asp?articlekey=11508"]hyperactivity[/URL], [URL="http://www.excelmale.com/script/main/art.asp?articlekey=13097"]somnolence[/URL] and [URL="http://www.excelmale.com/script/main/art.asp?articlekey=5919"]urticaria[/URL]. When administered intravenously for diagnostic use, the following adverse reactions have been noted: flushing of the face, injection site pain, redness and/or swelling, [URL="http://www.excelmale.com/script/main/art.asp?articlekey=4510"]nausea[/URL], headache, vomiting, dysgeusia, pallor and tightness in the [URL="http://www.excelmale.com/script/main/art.asp?articlekey=19270"]chest[/URL]. [h=4]Drug Abuse and Dependence[/b] The clinical pharmacology suggests that Sermorelin is very unlikely to be associated with drug abuse or dependence and there have been no reports of this from clinical trials. [URL]http://www.rxlist.com/sermorelin-acetate-drug/side-effects-interactions.htm[/URL] [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Question regarding allergic reaction after injecting Sermorelin
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