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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about testosterone level and constant tiredness
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<blockquote data-quote="Vettester Chris" data-source="post: 15162" data-attributes="member: 696"><p>Thanks for posting labs ... What you have posted can actually be a great learning tool for EVERYONE on the subject of the thyroid and "normality" ...</p><p></p><p>So many doctors will run the TSH lab as their first course of action to review a patient's thyroid. When a patient like yourself presents a 1.48 pmol result on the TSH, the vast majority of GPs and endos will close the book and say your thyroid is spot-on! As far as TSH goes, that's a sweet zone reading if there ever was one.</p><p></p><p>Sadly, that diagnosis would be anything but sweet! Reason, you fortunately pulled both FT3 & FT4 serum labs, which paint a different picture. Take note where your values fall within the reference ranges of both of these labs</p><p></p><p>FT3 is at 10.8% of the reference range</p><p>FT4 is at 33% of the reference range</p><p></p><p>Ideally, it would be great to see both of these values in the 50% to 80% range. It would be also good to see both values relatively close to each other in their respective ref ranges; meaning if your FT4 was at 58%, you might want to see your FT3 at/around the same, maybe mid 50 percentile, indicating a slightly higher amount of reserves with the T4. This isn't a mandatory thing, especially if treating hypothyroidism with exogenous T3 (Cytomel), whereas T4 will be bypassed and remain low. In some situations this is ideal, especially if T4 isn't adequately.</p><p></p><p> If the pituitary and feedback loop were fail proof, going by your T3 & T4 readings, <u>we should be seeing your TSH up in the 4's or 5's!</u> This isn't the case. TSH is spot-on, but your actual thyroid hormone levels are in the tank, FT3 being the critical hormone for getting to the cells to promote energy (ATP), metabolism of proteins, fats, carbs & even vitamins & essential nutrients. </p><p></p><p>There's a few other areas that need to be reviewed before getting too deep into what options you might explore .. We really need to see a Reverse T3 lab, plus the antibodies TPO & TgAb. My suspicion is adrenal issues with cortisol, with a possible slump in DHEA-S. Adrenal problems in many cases will reflect low & normal TSH values, but will also reveal low thyroid hormone levels, which is pretty much what we're seeing with your labs . </p><p></p><p>Would like to see a 4x saliva cortisol/DHEA-S report, where we can review the circadian profile, burden, and get an idea of what stage of potential adrenal fatigue you might be dealing with. Like the thyroid, it's a wide range for the reference range, so it's real easy for most doctors to discount any issue when they see the results landed somewhere between the low and the high. Like testosterone serum, 280ng/dl to 900ng/dl on a lab, and so many doctors will say you're normal if you have a 285 or a 885 .. Anyone in the know realizes this is not correct. </p><p></p><p>The adrenals are even a little more sensitive with how they should approached when reviewing the results, based on the variances of desired reference range intervals with each saliva tube specimen throughout the course of the day. If you can get these labs, I can provide you some feedback on the circadian profile, and the Cortisol/DHEA correlation summary, which will tell us how the adrenals are adapting with stress.</p><p></p><p> Depending on different stages of adrenal fatigue, pregnenolone steal could be factored, which in turn is neglecting hormone production ability downstream in areas like DHEA, estrogen & of course thyroid hormone. Get these labs and I'm sure more information about your situation can be discovered, which in turn can help you prepare a solid plan with your physician ...</p></blockquote><p></p>
[QUOTE="Vettester Chris, post: 15162, member: 696"] Thanks for posting labs ... What you have posted can actually be a great learning tool for EVERYONE on the subject of the thyroid and "normality" ... So many doctors will run the TSH lab as their first course of action to review a patient's thyroid. When a patient like yourself presents a 1.48 pmol result on the TSH, the vast majority of GPs and endos will close the book and say your thyroid is spot-on! As far as TSH goes, that's a sweet zone reading if there ever was one. Sadly, that diagnosis would be anything but sweet! Reason, you fortunately pulled both FT3 & FT4 serum labs, which paint a different picture. Take note where your values fall within the reference ranges of both of these labs FT3 is at 10.8% of the reference range FT4 is at 33% of the reference range Ideally, it would be great to see both of these values in the 50% to 80% range. It would be also good to see both values relatively close to each other in their respective ref ranges; meaning if your FT4 was at 58%, you might want to see your FT3 at/around the same, maybe mid 50 percentile, indicating a slightly higher amount of reserves with the T4. This isn't a mandatory thing, especially if treating hypothyroidism with exogenous T3 (Cytomel), whereas T4 will be bypassed and remain low. In some situations this is ideal, especially if T4 isn't adequately. If the pituitary and feedback loop were fail proof, going by your T3 & T4 readings, [U]we should be seeing your TSH up in the 4's or 5's![/U] This isn't the case. TSH is spot-on, but your actual thyroid hormone levels are in the tank, FT3 being the critical hormone for getting to the cells to promote energy (ATP), metabolism of proteins, fats, carbs & even vitamins & essential nutrients. There's a few other areas that need to be reviewed before getting too deep into what options you might explore .. We really need to see a Reverse T3 lab, plus the antibodies TPO & TgAb. My suspicion is adrenal issues with cortisol, with a possible slump in DHEA-S. Adrenal problems in many cases will reflect low & normal TSH values, but will also reveal low thyroid hormone levels, which is pretty much what we're seeing with your labs . Would like to see a 4x saliva cortisol/DHEA-S report, where we can review the circadian profile, burden, and get an idea of what stage of potential adrenal fatigue you might be dealing with. Like the thyroid, it's a wide range for the reference range, so it's real easy for most doctors to discount any issue when they see the results landed somewhere between the low and the high. Like testosterone serum, 280ng/dl to 900ng/dl on a lab, and so many doctors will say you're normal if you have a 285 or a 885 .. Anyone in the know realizes this is not correct. The adrenals are even a little more sensitive with how they should approached when reviewing the results, based on the variances of desired reference range intervals with each saliva tube specimen throughout the course of the day. If you can get these labs, I can provide you some feedback on the circadian profile, and the Cortisol/DHEA correlation summary, which will tell us how the adrenals are adapting with stress. Depending on different stages of adrenal fatigue, pregnenolone steal could be factored, which in turn is neglecting hormone production ability downstream in areas like DHEA, estrogen & of course thyroid hormone. Get these labs and I'm sure more information about your situation can be discovered, which in turn can help you prepare a solid plan with your physician ... [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about testosterone level and constant tiredness
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