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Again if blood health markers are good than it is highly unlikely running such doses in the short-term would be harmful and as far as long-term no one can say for sure.


Most of the minor cosmetic side-effects (oily skin/acne, MPH (genetically prone), water retention, gyno (genetically prone), testicular atrophy are usually temporary and can be controlled/managed to a certain degree through the use of ancillaries.


If anything long-term would be possible cardiovascular damage, liver damage (only with use of c-17 alpha alkylated orals) and permanent dysfunction of the hpta.


That said ones genetics/lifestyle would also play a big role.


Regardless of running higher doses even if blood health markers are good.....no healthy young male naturally produces T levels (TT/FT) that high 2000+


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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