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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about Sublingual Testosterone
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<blockquote data-quote="Jasen Bruce" data-source="post: 17388" data-attributes="member: 14"><p>Testosterone troches are not the best way to administer testosterone. it is very costly and most of the clinics who provide men testosterone in troche form do so because they can profit more from it.</p><p>First of all, testosterone does not absorb well sublingually. If you are lucky a small fraction of the total dosage will actually make it into the blood stream. Since testosterone in troche form is not alkylated, it will not survive metabolism in the liver and will be destroyed. I have worked in compounding and never heard of using an esterfied testosterone in troche form. Usually testosterone base (non estered) is used. Even with the propionate, the half-life will be cut short due to the difference in metabolism between SL and injection. There is zero data that an esterfied testosterone will even absorb sublingually, and as stated previously even non estered T will not absorb sufficiently in this way. When we experimented with SL testosterone troches a few years back, it took 100mg 3 times per day just to get total T to increase into a decent range, but even then it was towards the bottom of the range. </p><p></p><p>Troches have been used with some success in women since females require a smaller amount of testosterone, but even in women troches are the last resort. Topical cream and of course injection is preferred.</p></blockquote><p></p>
[QUOTE="Jasen Bruce, post: 17388, member: 14"] Testosterone troches are not the best way to administer testosterone. it is very costly and most of the clinics who provide men testosterone in troche form do so because they can profit more from it. First of all, testosterone does not absorb well sublingually. If you are lucky a small fraction of the total dosage will actually make it into the blood stream. Since testosterone in troche form is not alkylated, it will not survive metabolism in the liver and will be destroyed. I have worked in compounding and never heard of using an esterfied testosterone in troche form. Usually testosterone base (non estered) is used. Even with the propionate, the half-life will be cut short due to the difference in metabolism between SL and injection. There is zero data that an esterfied testosterone will even absorb sublingually, and as stated previously even non estered T will not absorb sufficiently in this way. When we experimented with SL testosterone troches a few years back, it took 100mg 3 times per day just to get total T to increase into a decent range, but even then it was towards the bottom of the range. Troches have been used with some success in women since females require a smaller amount of testosterone, but even in women troches are the last resort. Topical cream and of course injection is preferred. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about Sublingual Testosterone
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