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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about E2 and Testosterone Percentage in the Body
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<blockquote data-quote="rocket man 400" data-source="post: 174911" data-attributes="member: 40461"><p>let me show you my correspondence with Life Extension. they suggest anastrozole to maintain levels of E2 between 20-30. they do not sell this product. just very curious why most everyone suggests keeping E2 under control yet am hearing on a few forums that high E2 is beneficial. I am extremely interested in trying to see if I am fine without the Al. but which is the truth.. moderate E2 using Al to control estradiol or higher E2 ? I have read all about avoiding anasrozole and it sounds good... but still confused as the majority are saying control E2 in a moderate range. And have heard that regular doctors who know nothing about TRT and prescribe T don t care about E2 either.. something seems strange?</p><p>See below:</p><p></p><p>Thank you for your recent correspondence.</p><p></p><p>We are sorry to hear about the symptoms you are experiencing, and for any confusion. We are happy to provide our viewpoints on estradiol levels in men. Life Extension views blood levels of estradiol to be 20-30 pg/mL on a reference range of 7.6-42.6 pg/mL when using the ELCIA estradiol serum test by LabCorp to be optimal. This is because estradiol levels above and below this range have been linked with an elevated risk of mortality in men. Additionally, elevated estradiol levels above the reference range and linked with cardiovascular disease and prostate enlargement men. Levels that are below the reference range are linked with increased fracture risk. All of this data points to the need for estradiol to be healthy as a male but too much or too little being detrimental to long term health.</p><p></p><p>That range does not take into account a ratio of total testosterone to estradiol. This can also be important as both hormones work in unison to support libido, erections, mood, muscle mass, muscle recovery, glucose metabolism, cognition, and overall health. Life Extension views a total testosterone to estradiol ratio of around 23-40 to be optimal using LabCorp reference ranges. This can help point us toward an optimal for total testosterone levels being around 700-900 ng/dL on a reference range of 264-916 ng/dL when using a LabCorp test to maintain an ideal ratio.</p><p></p><p>We support the use of aromatase inhibiting medications if needed to help a male maintain an optimal total testosterone to estradiol ratio and optimal estradiol levels. Please note, if one’s reference ranges differ from the listed above, then the data provided may not apply as the information above only applies to LabCorp reference ranges. We suggest discussing these optimal ranges with your doctor to evaluate what numbers may apply to you to support your overall health. We do not suggest stopping your medication without talking to your doctor first. Here are links to articles and our protocols on Lab Testing and Male Hormone Restoration you can review with your doctor:</p><p></p><p><a href="https://www.lifeextension.com/magazine/2010/5/why-estrogen-balance-is-critical-to-aging-men?fbclid=IwAR3oheTkxkNymZw_y3RZAtViQY_QiEPS-BXSRONRhV96TWFWHxk9kQBMgQk" target="_blank">https://www.lifeextension.com/magazine/2010/5/why-estrogen-balance-is-critical-to-aging-men</a></p><p></p><p><a href="https://www.lifeextension.com/magazine/2008/11/dangers-of-excess-estrogen-in-the-aging-male?fbclid=IwAR1pD4EUwetGBC-PzIATbN7DG90qTKBpv16uybJpCpIsvxvqsjS2537kHdc" target="_blank">https://www.lifeextension.com/magazine/2008/11/dangers-of-excess-estrogen-in-the-aging-male</a></p><p></p><p><a href="https://l.facebook.com/l.php?u=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F15669538%3Ffbclid%3DIwAR3JDYqWiq-opg8LD274R-OrKQL9E8Q4xd3_QA_svEF8IK38s86auPAT61U&h=AT2_9sXP6Qauhh4VgeQt1D5rSByuGHShLN6FZRQdLwusAywLMG-s-swFdCP8QLO78e0NJ3-Fk1_HBVvEK5zDv_bSW5Pphfp2y6YFW9LVySLW0l_CkkXWL5Ht479W78zerIZu" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/15669538</a></p><p></p><p><a href="https://l.facebook.com/l.php?u=https%3A%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1111%2Fj.1743-6109.2005.00075.x%3Ffbclid%3DIwAR2E-H2UszIb0PGl9XeObtEpG8vTRAOmGnD79cx42G0BVnK57Yofb383Xm8&h=AT2_9sXP6Qauhh4VgeQt1D5rSByuGHShLN6FZRQdLwusAywLMG-s-swFdCP8QLO78e0NJ3-Fk1_HBVvEK5zDv_bSW5Pphfp2y6YFW9LVySLW0l_CkkXWL5Ht479W78zerIZu" target="_blank">https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1743-6109.2005.00075.x</a></p><p></p><p><a href="https://www.lifeextension.com/protocols/appendix/lab-testing?fbclid=IwAR2SQ1jlCPRwD6lKANt4iaWC_ArU0_7l21FmAiMnhdF13ileYFIFUEl1UyE" target="_blank">https://www.lifeextension.com/protocols/appendix/lab-testing</a></p><p></p><p><a href="https://www.lifeextension.com/protocols/male-reproductive/male-hormone-restoration?fbclid=IwAR1limQsRgYQl0s-bRet5qsiOzgbpEh4iCmRJT29mCoIkXBAFjmJdPdG58I" target="_blank">https://www.lifeextension.com/protocols/male-reproductive/male-hormone-restoration</a></p><p></p><p>Type a message...</p></blockquote><p></p>
[QUOTE="rocket man 400, post: 174911, member: 40461"] let me show you my correspondence with Life Extension. they suggest anastrozole to maintain levels of E2 between 20-30. they do not sell this product. just very curious why most everyone suggests keeping E2 under control yet am hearing on a few forums that high E2 is beneficial. I am extremely interested in trying to see if I am fine without the Al. but which is the truth.. moderate E2 using Al to control estradiol or higher E2 ? I have read all about avoiding anasrozole and it sounds good... but still confused as the majority are saying control E2 in a moderate range. And have heard that regular doctors who know nothing about TRT and prescribe T don t care about E2 either.. something seems strange? See below: Thank you for your recent correspondence. We are sorry to hear about the symptoms you are experiencing, and for any confusion. We are happy to provide our viewpoints on estradiol levels in men. Life Extension views blood levels of estradiol to be 20-30 pg/mL on a reference range of 7.6-42.6 pg/mL when using the ELCIA estradiol serum test by LabCorp to be optimal. This is because estradiol levels above and below this range have been linked with an elevated risk of mortality in men. Additionally, elevated estradiol levels above the reference range and linked with cardiovascular disease and prostate enlargement men. Levels that are below the reference range are linked with increased fracture risk. All of this data points to the need for estradiol to be healthy as a male but too much or too little being detrimental to long term health. That range does not take into account a ratio of total testosterone to estradiol. This can also be important as both hormones work in unison to support libido, erections, mood, muscle mass, muscle recovery, glucose metabolism, cognition, and overall health. Life Extension views a total testosterone to estradiol ratio of around 23-40 to be optimal using LabCorp reference ranges. This can help point us toward an optimal for total testosterone levels being around 700-900 ng/dL on a reference range of 264-916 ng/dL when using a LabCorp test to maintain an ideal ratio. We support the use of aromatase inhibiting medications if needed to help a male maintain an optimal total testosterone to estradiol ratio and optimal estradiol levels. Please note, if one’s reference ranges differ from the listed above, then the data provided may not apply as the information above only applies to LabCorp reference ranges. We suggest discussing these optimal ranges with your doctor to evaluate what numbers may apply to you to support your overall health. We do not suggest stopping your medication without talking to your doctor first. Here are links to articles and our protocols on Lab Testing and Male Hormone Restoration you can review with your doctor: [URL='https://www.lifeextension.com/magazine/2010/5/why-estrogen-balance-is-critical-to-aging-men?fbclid=IwAR3oheTkxkNymZw_y3RZAtViQY_QiEPS-BXSRONRhV96TWFWHxk9kQBMgQk']https://www.lifeextension.com/magazine/2010/5/why-estrogen-balance-is-critical-to-aging-men[/URL] [URL='https://www.lifeextension.com/magazine/2008/11/dangers-of-excess-estrogen-in-the-aging-male?fbclid=IwAR1pD4EUwetGBC-PzIATbN7DG90qTKBpv16uybJpCpIsvxvqsjS2537kHdc']https://www.lifeextension.com/magazine/2008/11/dangers-of-excess-estrogen-in-the-aging-male[/URL] [URL='https://l.facebook.com/l.php?u=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F15669538%3Ffbclid%3DIwAR3JDYqWiq-opg8LD274R-OrKQL9E8Q4xd3_QA_svEF8IK38s86auPAT61U&h=AT2_9sXP6Qauhh4VgeQt1D5rSByuGHShLN6FZRQdLwusAywLMG-s-swFdCP8QLO78e0NJ3-Fk1_HBVvEK5zDv_bSW5Pphfp2y6YFW9LVySLW0l_CkkXWL5Ht479W78zerIZu']https://www.ncbi.nlm.nih.gov/pubmed/15669538[/URL] [URL='https://l.facebook.com/l.php?u=https%3A%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1111%2Fj.1743-6109.2005.00075.x%3Ffbclid%3DIwAR2E-H2UszIb0PGl9XeObtEpG8vTRAOmGnD79cx42G0BVnK57Yofb383Xm8&h=AT2_9sXP6Qauhh4VgeQt1D5rSByuGHShLN6FZRQdLwusAywLMG-s-swFdCP8QLO78e0NJ3-Fk1_HBVvEK5zDv_bSW5Pphfp2y6YFW9LVySLW0l_CkkXWL5Ht479W78zerIZu']https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1743-6109.2005.00075.x[/URL] [URL='https://www.lifeextension.com/protocols/appendix/lab-testing?fbclid=IwAR2SQ1jlCPRwD6lKANt4iaWC_ArU0_7l21FmAiMnhdF13ileYFIFUEl1UyE']https://www.lifeextension.com/protocols/appendix/lab-testing[/URL] [URL='https://www.lifeextension.com/protocols/male-reproductive/male-hormone-restoration?fbclid=IwAR1limQsRgYQl0s-bRet5qsiOzgbpEh4iCmRJT29mCoIkXBAFjmJdPdG58I']https://www.lifeextension.com/protocols/male-reproductive/male-hormone-restoration[/URL] Type a message... [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Question about E2 and Testosterone Percentage in the Body
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