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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Public Service Announcement: "Piss Poor" Direct RIA fT measurement (HELP is on the way)
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<blockquote data-quote="tareload" data-source="post: 223788"><p>Hey Folks, thought I would update the graph for free T reference ranges based on LC-MS/MS+ED and compare with Labcorp's direct RIA fT reference range.</p><p></p><p>What the hell do you do with with your direct fT measurement if you want to compare with equibrium dialysis reference ranges? Take the Labcorp values in pg/ml and divide by 10 to get ng/dl. Then multiply by 6.67 to <a href="https://forums.t-nation.com/t/realistic-trt-recomp-progress/253389/3314" target="_blank"><em>transform</em></a> the direct fT measurement to the equilibrium dialysis scale.</p><p></p><p>[ATTACH=full]21779[/ATTACH]</p><p></p><p>Example and background / gory details here:</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/when-does-natural-production-return-when-stopping-trt.25192/post-223774[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/desperate-advice-needed-quickly-too-late.25271/post-223491[/URL]</p><p></p><p>Enjoy!</p><p></p><p>Repeat. Long story short, take your direct RIA fT measurement in pg/ml, divide by 10 and <a href="https://forums.t-nation.com/t/realistic-trt-recomp-progress/253389/3314" target="_blank">multiply by 6.7</a> to get your value in ng/dl and on the same scale parity wise as the ED reference methods (at least as best as we can for now). Of course it doesn't help that the ED methods haven't been standardized and don't always agree with each other. Imagine that, the US reference laboratories don't all agree on the upper reference range for fT based on LC-MS/MS+ED. But we can't exactly blame that on the poor little direct fT assay, can we?</p><p></p><p>You also can bracket your direct fT "transform" value by your calculated fT with Vermeulen and Tru-T and compare the 3 to give you a decent range for thought and comparison with ED reference ranges below. Fun, isn't it?</p><p></p><p>Updated graphs:</p><p>[ATTACH=full]21777[/ATTACH]</p><p></p><p>[ATTACH=full]21778[/ATTACH]</p><p>You can see Labcorp's direct fT lower reference range snaps into place along side Quest/Mayo/Labcorp/ARUP ED methods. Of course there is still discrepancies on the upper reference ranges for the various reference labs. <em>Tru-T (Zakharov 2015) still all by itself on the lower reference range (it must be lonely at the top of the bottom).</em></p></blockquote><p></p>
[QUOTE="tareload, post: 223788"] Hey Folks, thought I would update the graph for free T reference ranges based on LC-MS/MS+ED and compare with Labcorp's direct RIA fT reference range. What the hell do you do with with your direct fT measurement if you want to compare with equibrium dialysis reference ranges? Take the Labcorp values in pg/ml and divide by 10 to get ng/dl. Then multiply by 6.67 to [URL='https://forums.t-nation.com/t/realistic-trt-recomp-progress/253389/3314'][I]transform[/I][/URL] the direct fT measurement to the equilibrium dialysis scale. [ATTACH type="full" alt="1652458771551.png"]21779[/ATTACH] Example and background / gory details here: [URL unfurl="true"]https://www.excelmale.com/forum/threads/when-does-natural-production-return-when-stopping-trt.25192/post-223774[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/desperate-advice-needed-quickly-too-late.25271/post-223491[/URL] Enjoy! Repeat. Long story short, take your direct RIA fT measurement in pg/ml, divide by 10 and [URL='https://forums.t-nation.com/t/realistic-trt-recomp-progress/253389/3314']multiply by 6.7[/URL] to get your value in ng/dl and on the same scale parity wise as the ED reference methods (at least as best as we can for now). Of course it doesn't help that the ED methods haven't been standardized and don't always agree with each other. Imagine that, the US reference laboratories don't all agree on the upper reference range for fT based on LC-MS/MS+ED. But we can't exactly blame that on the poor little direct fT assay, can we? You also can bracket your direct fT "transform" value by your calculated fT with Vermeulen and Tru-T and compare the 3 to give you a decent range for thought and comparison with ED reference ranges below. Fun, isn't it? Updated graphs: [ATTACH type="full" alt="1652457239528.png"]21777[/ATTACH] [ATTACH type="full" alt="1652457248291.png"]21778[/ATTACH] You can see Labcorp's direct fT lower reference range snaps into place along side Quest/Mayo/Labcorp/ARUP ED methods. Of course there is still discrepancies on the upper reference ranges for the various reference labs. [I]Tru-T (Zakharov 2015) still all by itself on the lower reference range (it must be lonely at the top of the bottom).[/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Public Service Announcement: "Piss Poor" Direct RIA fT measurement (HELP is on the way)
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