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Table 2. Baseline Evaluation of Prostate Health in Men with Hypogonadism Being Evaluated for Consideration of Testosterone Replacement Therapy

1) Evaluate Prostate Cancer Risk

a) Elicit history of:

i) Prostate cancer

ii) Prostate cancer in first degree siblings

iii) Prostate biopsy

iv) prostate surgery

b) Perform digital prostate examination

c) Measure baseline PSA level in men 55 to 70 years of age

d) Consider using an on-line tool such as the Prostate Cancer Prevention Trial Risk Calculator to compute baseline risk of prostate cancer

2) Evaluate lower urinary tract symptoms:

a) International Prostate Symptom Scale score

b) Medications for lower urinary tract symptoms

c) History of surgery for benign prostatic hyperplasia

<blockquote data-quote="madman" data-source="post: 282968" data-attributes="member: 13851">Table 2. Baseline Evaluation of Prostate Health in Men with Hypogonadism Being Evaluated for Consideration of Testosterone Replacement Therapy1) Evaluate Prostate Cancer Risk&nbsp;a) Elicit history of:&nbsp;i) Prostate cancerii) Prostate cancer in first degree siblings iii) Prostate biopsyiv) prostate surgeryb) Perform digital prostate examinationc) Measure baseline PSA level in men 55 to 70 years of age d) Consider using an on-line tool such as the Prostate Cancer Prevention Trial Risk Calculator to compute baseline risk of prostate cancer2) Evaluate lower urinary tract symptoms:a) International Prostate Symptom Scale score b) Medications for lower urinary tract symptoms c) History of surgery for benign prostatic hyperplasia</blockquote>

[QUOTE="madman, post: 282968, member: 13851"] [B]Table 2. Baseline Evaluation of Prostate Health in Men with Hypogonadism Being Evaluated for Consideration of Testosterone Replacement Therapy 1) Evaluate Prostate Cancer Risk a) Elicit history of:[/B] i) Prostate cancer ii) Prostate cancer in first degree siblings iii) Prostate biopsy iv) prostate surgery [B]b) Perform digital prostate examination c) Measure baseline PSA level in men 55 to 70 years of age d) Consider using an on-line tool such as the Prostate Cancer Prevention Trial Risk Calculator to compute baseline risk of prostate cancer 2) Evaluate lower urinary tract symptoms: a) International Prostate Symptom Scale score b) Medications for lower urinary tract symptoms c) History of surgery for benign prostatic hyperplasia[/B] [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038