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Chapters Timeline:

4:48  Physical activity and exercise are important to make you feel better plus mental health booster

5:31  What comes to mind from the Genetics lecture?

9:24  How does liquid biopsies relate to early screening?

14:29  15-20 years ago total body CT scans not finding actionable cancer-MRI's now can

18:25  The problem of over diagnosed Prostate Cancer

19:05  Active Surveillance - why isn't every man tested for BRCA mutations?

23:16  How does being BRCA positive correlate with treatment in breast vs prostate cancer?

27:25  Random biopsies - root cause of over treatment until 2015

28:26  How does MRI replace biopsies in liver cancer? What about Prostate? PET scans?

30:53  Information is evolving too fast for one person to keep track of

31:25  GINA - Genetic Information Nondiscrimination Act 2009

32:58  Statistics show mortality rates for men with 3+3 PCa is lower than general population

34:10  Lynch Syndrome

38:05  Familial Hypercholesterolemia

39:09  Sharks and Minnows

42:52  70% of men with PSA above 4 will never get diagnosed with prostate cancer

43:41  Gadolinium contrast agent - yes or no?

44:09  MRI second opinions

48:00  MRI's can miss up to 20% of clinically significant cancers but...

49:01  Historical reason for going off active surveillance

51:02  New role for PSMA test

53:39  Around one half of men with high gleason scores will never metastasize

56:43  PSMA scans can now pick up small amounts of cancer

58:59  MRI's and PSMA scans

1:03:36  How often can MRI complement PSMA?

1:04:12  DIY Combat Manual

1:06:27  Different types of Stage 4 cancer

1:08:03  Insurance and pharmaceutical company appeals

1:12:01  Follow up - Plan B

1:15:39  Hormone resistant men with treatments from Dr. Kwon

1:17:20  Law of probability - clinical trials

1:23:11  Sharks and minnows

1:24:11  How close is a clinical trial to completion and success?

1:30:24  For some Medicare covers drugs for high cardio event risk patients

1:32:40  What are the downsides and cautions of some drugs?

1:34:39  How does lifestyle effect drugs?

1:37:25  The more you exercise the bigger the reward

1:41:39  Active surveillance patients improved with exercise  - ERASE 2022 randomized trial

1:43:10  "I did all these healthy things and I still got cancer?"

1:46:27  You can benefit in a multitude of ways with exercise/taking care of yourself

1:53:01  We are cars

1:55:42  When a doctor says exercise makes a difference you should believe it

2:02:05  Diet questions