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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Propecia thoughts
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<blockquote data-quote="Matthew1975" data-source="post: 140252" data-attributes="member: 16306"><p>Cipro and Levaquin used to be standard protocol for certain infections, now they have Black Box warnings and are to be used only if a different antibiotic cannot be used or there is simply nothing else indicated due to the severity of the infection.</p><p></p><p>Something to remember about drugs and how they are approved.</p><p></p><p>Clinical trials are set up and run by the pharmaceutical companies. Many people are under the impression that the FDA has a team of researchers that run clinical trials and thus are responsible for the data, reporting, and conclusions of such trials. It should be known, that the drug companies run the clinical trials, collect and collate the data, and FDA reviews what is provided to them by the drug companies. Drug companies can carefully exclude patients that "upon further review, do not meet criteria to be included in the trial".</p><p></p><p>This PubMed abstract of a meta-analysis finds that the studies involving the safety reporting of finasteride are inadequate and are likely biased.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/25830296#" target="_blank">Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis. - PubMed - NCBI</a></p><p></p><p>Here is a link to the full article.</p><p></p><p><a href="https://jamanetwork.com/journals/jamadermatology/fullarticle/2212246" target="_blank">Adverse Event Reporting in Clinical Trials of Finasteride for Alopecia</a></p><p></p><p>Vioxx, Baycol, Fenfluramine, Seldane, Darvocet, Meridia, Rezulin, Bextra, Pergoglide, among others, were all at one point FDA approved without restriction, all have since been banned.</p><p></p><p>I have no reason to doubt my former co-worker at work, as a biochemist who worked on Propecia, he warned me because of his direct knowledge of the product, but couldn't be specific in his warnings as it could cost him his career if I decided to say "Hey, C*** R*** told me the following about Propecia."</p><p></p><p>I stand by what I said before, and I also agree with Vitamin_C: I believe in medication autonomy, and would much rather be physically healthy and look and feel better than I would have a good head of hair, but have my health suffer.</p><p></p><p>As long as prescribers have a detailed discussion with people who want to use medications such as finasteride and dutasteride for such things as androgenic alopecia, which while unfortunate, is not a life-threatening condition, then it comes down to the client wanting the drug and the clinical judgement of the prescriber as to whether they are okay with issuing a prescription for the drug.</p></blockquote><p></p>
[QUOTE="Matthew1975, post: 140252, member: 16306"] Cipro and Levaquin used to be standard protocol for certain infections, now they have Black Box warnings and are to be used only if a different antibiotic cannot be used or there is simply nothing else indicated due to the severity of the infection. Something to remember about drugs and how they are approved. Clinical trials are set up and run by the pharmaceutical companies. Many people are under the impression that the FDA has a team of researchers that run clinical trials and thus are responsible for the data, reporting, and conclusions of such trials. It should be known, that the drug companies run the clinical trials, collect and collate the data, and FDA reviews what is provided to them by the drug companies. Drug companies can carefully exclude patients that "upon further review, do not meet criteria to be included in the trial". This PubMed abstract of a meta-analysis finds that the studies involving the safety reporting of finasteride are inadequate and are likely biased. [URL='https://www.ncbi.nlm.nih.gov/pubmed/25830296#']Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis. - PubMed - NCBI[/URL] Here is a link to the full article. [URL='https://jamanetwork.com/journals/jamadermatology/fullarticle/2212246']Adverse Event Reporting in Clinical Trials of Finasteride for Alopecia[/URL] Vioxx, Baycol, Fenfluramine, Seldane, Darvocet, Meridia, Rezulin, Bextra, Pergoglide, among others, were all at one point FDA approved without restriction, all have since been banned. I have no reason to doubt my former co-worker at work, as a biochemist who worked on Propecia, he warned me because of his direct knowledge of the product, but couldn't be specific in his warnings as it could cost him his career if I decided to say "Hey, C*** R*** told me the following about Propecia." I stand by what I said before, and I also agree with Vitamin_C: I believe in medication autonomy, and would much rather be physically healthy and look and feel better than I would have a good head of hair, but have my health suffer. As long as prescribers have a detailed discussion with people who want to use medications such as finasteride and dutasteride for such things as androgenic alopecia, which while unfortunate, is not a life-threatening condition, then it comes down to the client wanting the drug and the clinical judgement of the prescriber as to whether they are okay with issuing a prescription for the drug. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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