I only read the abstract, but that’s definitely interesting. But also super confusing at the same time. They say at the beginning of the abstract that allopregnenolone increases anxiety, but I thought it was common knowledge that allopregnenolone was like the body’s natural xanax, and helps decrease anxiety.
Also, pregnenolone is known to improve cognitive function, and one of pregnenolone’s main metabolites is obv progesterone. So not sure how prog can decrease cognitive function when preg converts into it, yet preg usually improves cognitive function. Only thing I can think of is that prog can decrease cognitive function if the dose causes levels to be out of balance
But I’ve been experiencing a bit more finger tingling/ mild numbness than usual lately. I’m using HGH, but lowered my dose down to a dose that doesn’t cause me to have that side effect. And it worked for months. But recently it’s coming back a little, even on the same HGH dose. So I’m gonna do a quick experiment and drop my prog and see if it improves. Thanks for ur anecdote about oral prog clearly increasing water retention for u. Can’t deny real world results, regardless of what the literature states
