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I don’t think it works that way, generally cortisol peaks in the am and goes down at night, it doesn’t mean that if you take Prog at night it will convert into cortisol immediately, in order words, I believe circadian rhythm is what dictates the production of cortisol. However, taking Pregnenolone at night, for my self can be a hit or miss, it is ether calming or it does feel like producing  a energy similar to cortisol.

 I now do well with the Progesterone cream 12.5mg at night, I actually felt last week I lost some benefits on sleep and calmness during the day I noticed in the beginning, I may try to go up in dose. My Progesterone serum in the am came back at .4 on the Labcorp scale