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Interesting paper...

Serum ionized magnesium and calcium
and sex hormones in healthy young men:
importance of serum progesterone level

FERTILITY AND STERILITYt
VOL. 72, NO. 5, NOVEMBER 1999
American Society for Reproductive Medicine

"Given that the levels of Mg (magnesium) and total Mg in the menopausal
women were inversely related to the concentrations of
estrogen (7), it was surprising that the levels of Mg in the
men were directly and significantly related to the levels of
progesterone (P,.05) (Fig. 1). In addition, the Ca/Mg
ratios were inversely related to the progesterone concentrations
(P,.05) (Fig. 2). These significant relations between
progesterone and Mg levels as well as the Ca/Mg
ratios did not seem to be affected by the racial composition
of our population, at least with respect to whites and blacks.
The number of Asians (n 5 3) was too small to use for a
statistically valid pool. We found no relations or correlations
(P..05) between levels of the cations and testosterone or
estrogen or between levels of the sex steroids and total Mg
in young men, either at face value or normalized for body
mass index."

[ATTACH=full]15869[/ATTACH]

Is this one of the mechanisms that explain why Mg tends to help sleep and relaxation?

<blockquote data-quote="Nelson Vergel" data-source="post: 206099" data-attributes="member: 3">Interesting paper...Serum ionized magnesium and calciumand sex hormones in healthy young men:importance of serum progesterone levelFERTILITY AND STERILITYtVOL. 72, NO. 5, NOVEMBER 1999American Society for Reproductive Medicine&quot;Given that the levels of Mg (magnesium) and total Mg in the menopausalwomen were inversely related to the concentrations ofestrogen (7), it was surprising that the levels of Mg in themen were directly and significantly related to the levels ofprogesterone (P,.05) (Fig. 1). In addition, the Ca/Mgratios were inversely related to the progesterone concentrations(P,.05) (Fig. 2). These significant relations betweenprogesterone and Mg levels as well as the Ca/Mgratios did not seem to be affected by the racial compositionof our population, at least with respect to whites and blacks.The number of Asians (n 5 3) was too small to use for astatistically valid pool. We found no relations or correlations(P..05) between levels of the cations and testosterone orestrogen or between levels of the sex steroids and total Mgin young men, either at face value or normalized for bodymass index.&quot;[ATTACH=full]15869[/ATTACH]Is this one of the mechanisms that explain why Mg tends to help sleep and relaxation?</blockquote>

[QUOTE="Nelson Vergel, post: 206099, member: 3"] Interesting paper... [B]Serum ionized magnesium and calcium and sex hormones in healthy young men: importance of serum progesterone level[/B] FERTILITY AND STERILITYt VOL. 72, NO. 5, NOVEMBER 1999 American Society for Reproductive Medicine "Given that the levels of Mg (magnesium) and total Mg in the menopausal women were inversely related to the concentrations of estrogen (7), it was surprising that the levels of [B]Mg in the men were directly and significantly related to the levels of progesterone[/B] (P,.05) (Fig. 1). In addition, the Ca/Mg ratios were inversely related to the progesterone concentrations (P,.05) (Fig. 2). These significant relations between progesterone and Mg levels as well as the Ca/Mg ratios did not seem to be affected by the racial composition of our population, at least with respect to whites and blacks. The number of Asians (n 5 3) was too small to use for a statistically valid pool. We found no relations or correlations (P..05) between levels of the cations and testosterone or estrogen or between levels of the sex steroids and total Mg in young men, either at face value or normalized for body mass index." [ATTACH type="full" alt="progesterone and magnesium.jpg"]15869[/ATTACH] Is this one of the mechanisms that explain why Mg tends to help sleep and relaxation? [/QUOTE]

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038