Absolutely it can. When I was running 250mg/week(not TRT) for training purposes, did that for 3 years straight, I was having damn headaches pretty much everyday. But I also had other blood markers elevated that showed I had issues going on that needed fixing and most likely was the cause or contributting to it. Now off TRT for 8 months and headaches are a rare thing considering I follow my blueprint and not deviate from it. Honestly to be able to figure it out- context is all that matters. Hydration, food, sleep, stress, other drugs, BP, BG and so on.
