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I've tested out transdermal preg again for a couple months and while I do feel a bit better on it, the water retention is unbearable.  I should also mention that I'm tolerating dhea and preg better since switching to eod testosterone.  I can't explain why, but it's interesting.   I'll be trying sublingual preg instead starting Monday because dhea alone makes me lazy and lethargic, but it does bring down my blood pressure and anxiety so I can tell it's part of the problem.