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It made me tired with lots of uneasy energy inside for a few hours each day, but it wasn’t consistent.  I stopped after 3 days and am waiting for transdermal preg and DHEA.  I gained water weight with it too and believe it elevated e2 too high, but the way I felt I wouldn’t wait to see on a blood test.  The other thing though was at times I felt great and things that used to bother me didn’t anymore.  So, some pros and some cons.  I’m hoping the transdermal makes the difference.  I can’t really say much more than that because it was only 3 days, but 3 days was enough to know what was happening was not a sustainable way to live.