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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Pregnenolone Blood Levels
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<blockquote data-quote="Dr Justin Saya MD" data-source="post: 44182" data-attributes="member: 12687"><p>I think "inaccurate" may have multiple meanings in this context.</p><p></p><p>I wouldn't say the LC/MS-MS pregnenolone test is inaccurate - in the sense of giving a false reading - indeed it is fairly "accurate" in this sense based on the methodology.</p><p></p><p>However, the results may be "inaccurate" (not the best term but using it here to fit this discussion) in the sense that pregnenolone levels can vary WIDELY even on an INTRAday basis based on the rate/magnitude of how the pregnenolone is being "pulled" down the various downstream hormone pathways. </p><p></p><p>To even have a chance to get a true idea of the pregnenolone level and WHERE it may be going, one would need to concurrently check/monitor the other downstream hormones - DHEA-S, progesterone, cortisol X 4, aldosterone (with progesterone being a big one). </p><p></p><p>Thus, due to this complexity of multi-variable monitoring and also confounding variables, monitoring and evaluating subjective/symptomatic response is of utmost clinical importance.</p></blockquote><p></p>
[QUOTE="Dr Justin Saya MD, post: 44182, member: 12687"] I think "inaccurate" may have multiple meanings in this context. I wouldn't say the LC/MS-MS pregnenolone test is inaccurate - in the sense of giving a false reading - indeed it is fairly "accurate" in this sense based on the methodology. However, the results may be "inaccurate" (not the best term but using it here to fit this discussion) in the sense that pregnenolone levels can vary WIDELY even on an INTRAday basis based on the rate/magnitude of how the pregnenolone is being "pulled" down the various downstream hormone pathways. To even have a chance to get a true idea of the pregnenolone level and WHERE it may be going, one would need to concurrently check/monitor the other downstream hormones - DHEA-S, progesterone, cortisol X 4, aldosterone (with progesterone being a big one). Thus, due to this complexity of multi-variable monitoring and also confounding variables, monitoring and evaluating subjective/symptomatic response is of utmost clinical importance. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
Pregnenolone Blood Levels
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