Pre TRT and Current Labs...About ready to give up.

Yort

New Member
Hello, I've been on TRT for about 4 months now with absolutely zero positive effects on my libido or energy. I'm 53 about 5'10" and 180 pounds. My dose was 100mg of testosterone cypionate weekly, but now I've been injecting 50mg twice weekly because of high estradiol. According to my current labs my testosterone levels have risen considerably yet I have experienced no effects, not even testicular atrophy.

I'm recently divorced and have been dating a very attractive young woman so I have been extremely concerned about my lack of libido and ED issues. I was hoping TRT would be the miracle cure that everyone claimed, but so far I've been disappointed.

Ive posted my pre-trt and current labs and was hoping for some advice going forward. I realize my lipids are out of whack but I have been addressing this issue with dieting and exercise. Thanks
 

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I glanced over your labs. They look pretty good, except for your high estrogen and I missed your SHPG. It looks like your estrogen was high before it started TRT. I wonder if lowering it would help?Let me look for a post or I should say thread.
 
You could give dim a shot.
 
Thank you for posting your well-thought labs. SHBG is probably in the normal range - in the pre TRT labs there is a good Free T value with a slightly low total T.

TRT allegedly has more profound effects on people that were really low on free testosterone, and you weren't to begin with.

There is no drug that consistently raises libido but it is affected negatively by stress (too much work) and psychologically by a not so positive self/body image.
 
I glanced over your labs. They look pretty good, except for your high estrogen and I missed your SHPG. It looks like your estrogen was high before it started TRT. I wonder if lowering it would help?Let me look for a post or I should say thread.
Thanks for your reply...I'm definitely going to try DIM and I'll report back in a few weeks.

Thank you for posting your well-thought labs. SHBG is probably in the normal range - in the pre TRT labs there is a good Free T value with a slightly low total T.

TRT allegedly has more profound effects on people that were really low on free testosterone, and you weren't to begin with.

There is no drug that consistently raises libido but it is affected negatively by stress (too much work) and psychologically by a not so positive self/body image.
Thanks for your reply...Actually I started TRT with my doctor and she took two testosterone tests which were low (288). For some reason the Quest test showed a higher testosterone level...maybe because I was taking Biotin at the time.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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