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Platelet-Rich Fibrin Matrix Injections Help Men with Hair Loss
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<blockquote data-quote="Nelson Vergel" data-source="post: 8098" data-attributes="member: 3"><p><strong>[ATTACH]761[/ATTACH]</strong></p><p><strong></strong></p><p><strong>Platelet-Rich Fibrin Matrix (PRFM) for Androgenetic Alopecia.</strong></p><p></p><p><strong>Authors</strong></p><p></p><p>Sclafani AP.</p><p><strong>Journal</strong></p><p></p><p>Facial Plast Surg. 2014 Apr;30(2):219-24. doi: 10.1055/s-0034-1371896. Epub 2014 May 8.</p><p><strong>Affiliation</strong></p><p></p><p></p><p><strong>Abstract</strong></p><p></p><p>The objective of this study was to determine the effect of platelet-rich fibrin matrix (PRFM) treatment on androgenetic alopecia. Prospective cohort study of 15 (9 male and 6 female) subjects with androgenetic alopecia for at least 1 year who were treated with intradermal injections of autologous PRFM three times on a monthly basis. Hair density indices were measured in triplicate in the same area of the scalp before the treatment and 1, 2, 3 and 6 months after initial treatment. Hair density index (HDI) measurements were obtained and compared with pretreatment values for each subject. After a series of three intradermal PRFM injections, hair density indices increased significantly at 2 (47.4 ± 22.7%, p = 0.0031) and 3 (106.4 ± 56.9%, p = 0.0277, paired t-test) months after the initial treatment, and approached statistical significance at 6 months (75.1 ± 46.82%, p = 0.0606) after the initial treatment. Patients who achieved greater than 25% increase in HDI by 2 months after the initial treatment were more likely to have greater than 25% improvement at 6 months after the initial treatment (100 vs. 16.7%, p = 0.0476). Androgenetic alopecia affects a significant number of both men and women. A series of intradermal injections of autologous PRFM increased the HDI in patients with androgenetic alopecia at 2 and 3 months after initial treatment; this improvement approached statistical significance at 6 months after initiating treatment. Autologous PRFM injections may be a valuable treatment for androgenetic alopecia, particularly in cases with mild hair loss. The level of evidence is level 2.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 8098, member: 3"] [B][ATTACH=CONFIG]761[/ATTACH] Platelet-Rich Fibrin Matrix (PRFM) for Androgenetic Alopecia.[/B] [B]Authors[/B] Sclafani AP. [B]Journal[/B] Facial Plast Surg. 2014 Apr;30(2):219-24. doi: 10.1055/s-0034-1371896. Epub 2014 May 8. [B]Affiliation[/B] [B]Abstract[/B] The objective of this study was to determine the effect of platelet-rich fibrin matrix (PRFM) treatment on androgenetic alopecia. Prospective cohort study of 15 (9 male and 6 female) subjects with androgenetic alopecia for at least 1 year who were treated with intradermal injections of autologous PRFM three times on a monthly basis. Hair density indices were measured in triplicate in the same area of the scalp before the treatment and 1, 2, 3 and 6 months after initial treatment. Hair density index (HDI) measurements were obtained and compared with pretreatment values for each subject. After a series of three intradermal PRFM injections, hair density indices increased significantly at 2 (47.4 ± 22.7%, p = 0.0031) and 3 (106.4 ± 56.9%, p = 0.0277, paired t-test) months after the initial treatment, and approached statistical significance at 6 months (75.1 ± 46.82%, p = 0.0606) after the initial treatment. Patients who achieved greater than 25% increase in HDI by 2 months after the initial treatment were more likely to have greater than 25% improvement at 6 months after the initial treatment (100 vs. 16.7%, p = 0.0476). Androgenetic alopecia affects a significant number of both men and women. A series of intradermal injections of autologous PRFM increased the HDI in patients with androgenetic alopecia at 2 and 3 months after initial treatment; this improvement approached statistical significance at 6 months after initiating treatment. Autologous PRFM injections may be a valuable treatment for androgenetic alopecia, particularly in cases with mild hair loss. The level of evidence is level 2. [/QUOTE]
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Platelet-Rich Fibrin Matrix Injections Help Men with Hair Loss
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