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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Pharmacogenomics
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<blockquote data-quote="BigTex" data-source="post: 221616" data-attributes="member: 43589"><p>I used testosterone undeconate injectable for many years. I injected 750mg every 12 weeks. People thought i was nuts when I told them I had a serum level of 921 at the end of a 12 week cycle. How could this be? When I was a competitive world class powerlifter I also only used 250mg of testosterone enanthate and was one of the tops' in the world in two different weight classes. More recently my doctor prescribed me 200mg of testosterone cypionate every 10 days and I again tested and had a 2103 serum level. I was kind of shocked to say the least. But could it be that some of us genetically metabolize drugs quite differently that others. </p><p></p><p>Pharmacogenomics is a relatively new field of study which is a combination of pharmacology and genomics. Technically, Pharmacogenomics analyzes how the genetic makeup of an individual affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics (effects mediated through a drug's biological targets). So Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficiency with minimal adverse effects.</p><p></p><p>I know this type of study is done at the Cleveland Clinic or PGx testing typically involves taking either a small blood sample or a saliva sample. Specifically, the DNA in the sample will be extracted and examined with a process known as DNA sequencing. Very exciting field of study and I hope to have this done sometime in the future. Could explain why a few of us get very good results with very little amounts of drugs.</p><p></p><p>Here is a place here in Houston that does this testing</p><p>[URL unfurl="true"]https://tesistexas.com/[/URL]</p></blockquote><p></p>
[QUOTE="BigTex, post: 221616, member: 43589"] I used testosterone undeconate injectable for many years. I injected 750mg every 12 weeks. People thought i was nuts when I told them I had a serum level of 921 at the end of a 12 week cycle. How could this be? When I was a competitive world class powerlifter I also only used 250mg of testosterone enanthate and was one of the tops' in the world in two different weight classes. More recently my doctor prescribed me 200mg of testosterone cypionate every 10 days and I again tested and had a 2103 serum level. I was kind of shocked to say the least. But could it be that some of us genetically metabolize drugs quite differently that others. Pharmacogenomics is a relatively new field of study which is a combination of pharmacology and genomics. Technically, Pharmacogenomics analyzes how the genetic makeup of an individual affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics (effects mediated through a drug's biological targets). So Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficiency with minimal adverse effects. I know this type of study is done at the Cleveland Clinic or PGx testing typically involves taking either a small blood sample or a saliva sample. Specifically, the DNA in the sample will be extracted and examined with a process known as DNA sequencing. Very exciting field of study and I hope to have this done sometime in the future. Could explain why a few of us get very good results with very little amounts of drugs. Here is a place here in Houston that does this testing [URL unfurl="true"]https://tesistexas.com/[/URL] [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Pharmacogenomics
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