ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Pharmacogenetics of testosterone replacement therapy
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 226741" data-attributes="member: 13851"><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/variations-in-cag-repeats-of-men%E2%80%99s-androgen-receptor-gene.25036/#post-220020[/URL]</p><p></p><p><strong><em><strong>*The same applies to <u>androgen receptor gene CAG repeat lengths >24 in the presence of symptoms and normal testosterone levels</u> may be considered as a state of preclinical TD [93]</strong></em></strong></p><p><strong><em></em></strong></p><p><strong><em></em></strong></p><p><strong><em>*</em></strong><em>In humans, the AR gene comes in many forms, called alleles. The best-studied alleles are those involving a CAG repeat sequence that encodes a polyglutamine tract near the amino end of the androgen receptor. </em><strong><em>This CAG repeat has different lengths for different people. <u>In humans, the number of AR CAG repeats ranges from as few as 9 to as many as 36, but population averages are typically between 17 and 24</u> (Chamberlain et al., 1994; Hsiao et al., 1999; Irvine et al., 2000; La Spada et al., 1991). Individuals with higher numbers of AR CAG repeats will normally have diminished testosterone action on cellular functioning, effectively making males with high AR CAG repeats less masculine regarding most sexually dimorphic traits when compared to males with fewer AR CAG repeats (Loehlin et al., 2004; Simanainen et al., 2011)</em></strong></p><p><strong><em></em></strong></p><p><strong><em>* </em></strong><em><strong>Based on a total sample of 57,826 males occupying 78 countries, the <u>overall average number of AR CAG repeats was found to be 21.40</u>.</strong> National averages ranged from 17.00 to 23.16. Five countries had averages in the 17.00s; they were Swaziland (17.00), Zambia (17.00), Sierra Leone (17.30), Nigeria (17.58), and Senegal (17.90). Five countries had averages of 23.00 or higher; they were Lithuania (23.00), Mongolia (23.00), Ireland (23.07), Thailand (23.10), and Romania (23.16).</em></p></blockquote><p></p>
[QUOTE="madman, post: 226741, member: 13851"] [URL unfurl="true"]https://www.excelmale.com/forum/threads/variations-in-cag-repeats-of-men%E2%80%99s-androgen-receptor-gene.25036/#post-220020[/URL] [B][I][B]*The same applies to [U]androgen receptor gene CAG repeat lengths >24 in the presence of symptoms and normal testosterone levels[/U] may be considered as a state of preclinical TD [93][/B] *[/I][/B][I]In humans, the AR gene comes in many forms, called alleles. The best-studied alleles are those involving a CAG repeat sequence that encodes a polyglutamine tract near the amino end of the androgen receptor. [/I][B][I]This CAG repeat has different lengths for different people. [U]In humans, the number of AR CAG repeats ranges from as few as 9 to as many as 36, but population averages are typically between 17 and 24[/U] (Chamberlain et al., 1994; Hsiao et al., 1999; Irvine et al., 2000; La Spada et al., 1991). Individuals with higher numbers of AR CAG repeats will normally have diminished testosterone action on cellular functioning, effectively making males with high AR CAG repeats less masculine regarding most sexually dimorphic traits when compared to males with fewer AR CAG repeats (Loehlin et al., 2004; Simanainen et al., 2011) * [/I][/B][I][B]Based on a total sample of 57,826 males occupying 78 countries, the [U]overall average number of AR CAG repeats was found to be 21.40[/U].[/B] National averages ranged from 17.00 to 23.16. Five countries had averages in the 17.00s; they were Swaziland (17.00), Zambia (17.00), Sierra Leone (17.30), Nigeria (17.58), and Senegal (17.90). Five countries had averages of 23.00 or higher; they were Lithuania (23.00), Mongolia (23.00), Ireland (23.07), Thailand (23.10), and Romania (23.16).[/I] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Pharmacogenetics of testosterone replacement therapy
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top