ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
ExcelFemale
HRT in Women
Pharmaceutical and Energy-Based Management of Sexual Problems in Women
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 209796" data-attributes="member: 13851"><p><strong><u>Hormonal Medications</u>: a Blast From the Past </strong></p><p></p><p><em><strong>The pharmaceutical industry’s most recent forays into the treatment of FSD have had somewhat ambiguous results. <u>PDE5i medications</u> target the genitalia to boost arousal response without adequately addressing the cognitive or emotional aspects of sexual function. <u>Flibanserin and bremelanotide</u> target the CNS, to produce only slight improvements in sexual interest and responsiveness when compared with placebo. An alternative to these is the off-label use of older, <u>hormonal medications</u>, which act simultaneously on mind and body. It is not surprising that pioneering sexologist William Masters began his clinical research career in the 1940s with a focus on the<u> positive effects of estrogen replacement therapy on hypogonadal women</u>.47 <u>At the same time, androgens were also studied and used in women for the treatment of various medical problems, including sexual dysfunction</u>.48 <u>Both sex steroids act within the CNS to stimulate sexual appetite31 and within the genitalia to maintain vulvovaginal tissue integrity</u>.49</strong></em></p><p></p><p><strong><em>Testosterone therapy, in isolation and in combination with estrogen (and sometimes progesterone), has been shown in many randomized controlled trials to increase sexual desire and satisfaction in postmenopausal women with HSDD.50</em></strong><em><strong> <u>Clinical application of these data remains a persistent challenge because it remains uncertain</u>: (<u>1</u>) to what degree testosterone, and not the estrogen into which it may be aromatized, is the relevant actor51; (<u>2</u>) whether testosterone supplementation might safely and effectively address sexual problems in premenopausal women52; and (<u>3</u>) how to most reliably dose this medication in a regulatory and financial environment that discourages the development of testosterone products for women.53</strong></em><strong><em> <u>The risk of AEs</u>, including hirsutism, acne, vocal changes, and clitoromegaly, is necessarily increased when products intended to produce adult male levels of testosterone are prescribed for women.54 <u>The probability of these AEs</u> is reduced with careful monitoring and dose titration to maintain free testosterone within the normal female range,55,56 but the optimal testosterone regimen for women has yet to be determined.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 209796, member: 13851"] [B][U]Hormonal Medications[/U]: a Blast From the Past [/B] [I][B]The pharmaceutical industry’s most recent forays into the treatment of FSD have had somewhat ambiguous results. [U]PDE5i medications[/U] target the genitalia to boost arousal response without adequately addressing the cognitive or emotional aspects of sexual function. [U]Flibanserin and bremelanotide[/U] target the CNS, to produce only slight improvements in sexual interest and responsiveness when compared with placebo. An alternative to these is the off-label use of older, [U]hormonal medications[/U], which act simultaneously on mind and body. It is not surprising that pioneering sexologist William Masters began his clinical research career in the 1940s with a focus on the[U] positive effects of estrogen replacement therapy on hypogonadal women[/U].47 [U]At the same time, androgens were also studied and used in women for the treatment of various medical problems, including sexual dysfunction[/U].48 [U]Both sex steroids act within the CNS to stimulate sexual appetite31 and within the genitalia to maintain vulvovaginal tissue integrity[/U].49[/B][/I] [B][I]Testosterone therapy, in isolation and in combination with estrogen (and sometimes progesterone), has been shown in many randomized controlled trials to increase sexual desire and satisfaction in postmenopausal women with HSDD.50[/I][/B][I][B] [U]Clinical application of these data remains a persistent challenge because it remains uncertain[/U]: ([U]1[/U]) to what degree testosterone, and not the estrogen into which it may be aromatized, is the relevant actor51; ([U]2[/U]) whether testosterone supplementation might safely and effectively address sexual problems in premenopausal women52; and ([U]3[/U]) how to most reliably dose this medication in a regulatory and financial environment that discourages the development of testosterone products for women.53[/B][/I][B][I] [U]The risk of AEs[/U], including hirsutism, acne, vocal changes, and clitoromegaly, is necessarily increased when products intended to produce adult male levels of testosterone are prescribed for women.54 [U]The probability of these AEs[/U] is reduced with careful monitoring and dose titration to maintain free testosterone within the normal female range,55,56 but the optimal testosterone regimen for women has yet to be determined.[/I][/B] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
ExcelFemale
HRT in Women
Pharmaceutical and Energy-Based Management of Sexual Problems in Women
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top