Peyronie Disease

madman

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Peyronie disease is a common, treatable medical condition that affects millions of men in the US



Peyronie disease (PD) is an abnormality of the erect penis such as a bend, curve, or hourglass-shaped narrowing which can negatively affect sexual function.
PD can cause pain (with or without erections), inability to engage in penetrative sexual intercourse, erectile dysfunction, emotional distress, depression, and relationship difficulties. It develops in up to 5% to 10% of men. PD occurs because of inflammation and scarring of the tunica albuginea, the inner lining of the penis that allows the penis to become hard during erections. This scarring is referred to as a Peyronie plaque. Development of PD may be genetic or related to an injury to the penis (which patients may not remember experiencing).




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Peyronie disease
The tunica albuginea is the inner lining of the penis that surrounds the corpus cavernosum and allows the penis to become hard during erections. Peyronie disease is inflammation or scarring of the tunica albuginea that causes a bend, curve, or hourglass-shaped narrowing of the erect penis that can negatively affect sexual function.

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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