Susan MacDonald, MD, Associate Professor of Urology, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, reviews the pathophysiology of Peyronie’s disease and outlines research directions for the future. She explains that Peyronie’s disease typically affects men in midlife, with deformities ranging from plaques to ossified lesions, and often results in erectile dysfunction. Associations with diabetes, prostatectomy, and Dupuytren contracture suggest a systemic fibrotic or autoimmune process.
Dr. MacDonald challenges the current...
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